4-ethyl-N-phenylbenzamide

Base Information

• Chemical Name: 4-ethyl-N-phenylbenzamide
• CAS No.: 84270-05-3
• Molecular Formula: C15H15NO
• Molecular Weight: 225.29
• Mol file: 84270-05-3.mol

Synonyms:4-ethyl-benzoic acid anilide;4-ethyl-N-phenylbenzamide;4-Aethyl-benzoesaeure-anilid;

Chemical Property of 4-ethyl-N-phenylbenzamide

Chemical Property:

• PSA: 29.10000
• LogP: 3.57430

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-ethyl-N-phenylbenzamide

There total 10 articles about 4-ethyl-N-phenylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.3%

p-ethylbenzoyl chloride (16331-45-6) + aniline (62-53-3) → 4-ethyl-N-phenyl benzamide (84270-05-3)

Guidance literature:

With pyridine; In chloroform; at 0 ℃; for 2h;

DOI:10.1016/j.bmc.2011.05.031

Reference yield: 90.0%

C15H14BrNO (842116-58-9) → 4-ethyl-N-phenyl benzamide (84270-05-3)

Guidance literature:

With 1-[2-(N-(3-diphenylphosphinopropyl))aminoethyl]pyrrolidine; triethylamine; palladium dichloride; In water; at 100 ℃; for 12h; regioselective reaction;

DOI:10.1055/s-0040-1707116

Reference yield: 86.0%

C15H14ClNO → 4-ethyl-N-phenyl benzamide (84270-05-3)

Guidance literature:

With 1-[2-(N-(3-diphenylphosphinopropyl))aminoethyl]pyrrolidine; triethylamine; palladium dichloride; In water; at 100 ℃; for 12h; regioselective reaction;

DOI:10.1055/s-0040-1707116

upstream raw materials:

4-ethyl-benzophenone-seqtrans-oxime

aniline

tebufenozide

4-ethylbenzophenone

Downstream raw materials:

2-(4-ethylphenyl)-1,3-benzoxazole

Refernces

• 1、 Gao, Hui,Li, Minxin,Mao, Zewei,Rao, Gaoxiong,Tang, Yanling. "Efficient Pd-Catalyzed Hydrodehalogenation of o -Haloanilides in Water". supporting information. p. 1121 - 1125. Retrieved 2020/07/03.
• 2、 Zhang, Jin,Ma, Yuqiang,Ma, Yangmin. "Synthesis of Secondary Amides through the Palladium(II)-Catalyzed Aminocarbonylation of Arylboronic Acids with Amines or Hydrazines and Carbon Dioxide". supporting information. p. 1720 - 1725. Retrieved 2018/04/24.