4-(Ethylthio)toluene

Base Information

• Chemical Name: 4-(Ethylthio)toluene
• CAS No.: 622-63-9
• Molecular Formula: C9H12S
• Molecular Weight: 152.26
• Hs Code.: 2930909090
• Mol file: 622-63-9.mol

Synonyms:4-(Ethylthio)toluene;Ethyl p-tolyl sulfide;1-(ethylthio)-4-methylbenzene;ethyl 4-methylphenyl sulfide;Benzene, 1-(ethylthio)-4-methyl-;Benzene,1-(ethylthio)-4-methyl;Ethyl p-cresyl sulfide;4-methylphenyl ethyl sulfide;p-Cresyl ethyl sulfide;Sulfide,ethyl p-tolyl;(4-tolyl)ethyl sulfide;1-(Ethylsulfanyl)-4-methylbenzene;ethyl-4-tolylsulfide;

Chemical Property of 4-(Ethylthio)toluene

Chemical Property:

• Vapor Pressure: 0.166mmHg at 25°C
• Melting Point: -45°C (estimate)
• Refractive Index: 1.5530
• Boiling Point: 220.6°Cat760mmHg
• Flash Point: 86°C
• PSA: 25.30000
• Density: 0.99g/cm³
• LogP: 3.10700

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(Ethylthio)toluene

There total 69 articles about 4-(Ethylthio)toluene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

ethyl bromide (74-96-4) + para-thiocresol (106-45-6) → ethyl p-tolyl sulfide (622-63-9)

Guidance literature:

With potassium carbonate; In acetone; at 20 ℃; for 20h;

DOI:10.1002/ejoc.201403105

Reference yield: 91.0%

C19H23OS(1+)*BF4(1-) → ethyl p-tolyl sulfide (622-63-9) + cyclopropyl phenyl ketone (3481-02-5)

Guidance literature:

With sodium hydroxide; In water; at 25 ℃; for 48h;

DOI:10.1039/P29820000579

Reference yield: 90.0%

4,4'-dimethyldiphenyliodonium fluoroborate + ethanethiol (75-08-1) → ethyl p-tolyl sulfide (622-63-9)

Guidance literature:

With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1081/SCC-100104008

upstream raw materials:

ethyl bromide

sodium p-thiocresolate

diethyl sulfate

diethyl ether

Downstream raw materials:

1-ethyl-4-(ethylthio)benzene

2,4-dimethyl-1-(ethylthio)benzene

Refernces

• 1、 Nakajima, Takumi,Takano, Ken,Maeda, Hiromu,Ogiwara, Yohei,Sakai, Norio. "Production of Alkyl Aryl Sulfides from Aromatic Disulfides and Alkyl Carboxylates via a Disilathiane–Disulfide Interchange Reaction". supporting information. p. 4103 - 4107. Retrieved 2021/11/10.
• 2、 Sakai, Norio,Maeda, Hiromu,Ogiwara, Yohei. "Copper-Catalyzed Three-Component Coupling Reaction of Aryl Iodides, a Disilathiane, and Alkyl Benzoates Leading to a One-Pot Synthesis of Alkyl Aryl Sulfides". . p. 2323 - 2330. Retrieved 2019/05/24.