Phenol,3,3'-(1,2-dibutyl-1,2-ethanediyl)bis- (9CI)

Base Information

• Chemical Name: Phenol,3,3'-(1,2-dibutyl-1,2-ethanediyl)bis- (9CI)
• CAS No.: 68266-27-3
• Molecular Formula: C22H30 O2
• Molecular Weight: 326.4724
• Mol file: 68266-27-3.mol

Synonyms:NSC 297172

Chemical Property of Phenol,3,3'-(1,2-dibutyl-1,2-ethanediyl)bis- (9CI)

Chemical Property:

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Phenol,3,3'-(1,2-dibutyl-1,2-ethanediyl)bis- (9CI)

There total 4 articles about Phenol,3,3'-(1,2-dibutyl-1,2-ethanediyl)bis- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

5,6-di-(3'-methoxyphenyl)-decane (68266-36-4) → 5,6-di-(3'-hydroxyphenyl)-decane (68266-27-3)

Guidance literature:

With pyridine hydrochloride; at 220 ℃;

DOI:10.1021/jm00142a014

Reference yield:

1-(3'-methoxyphenyl)-pentan-1-ol (60441-55-6) → 5,6-di-(3'-hydroxyphenyl)-decane (68266-27-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 64 percent / HCl (gas) / petroleum ether / -5 °C

2: 21 percent / CoCl₂, ethylmagnesium bromide / diethyl ether

3: 85 percent / pyridinium hydrochloride / 220 °C

With hydrogenchloride; ethylmagnesium bromide; pyridine hydrochloride; In diethyl ether; Petroleum ether;

DOI:10.1021/jm00142a014

Reference yield:

1-chlor-1-(3'-methoxyphenyl)-pentane (68266-35-3) → 5,6-di-(3'-hydroxyphenyl)-decane (68266-27-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 21 percent / CoCl₂, ethylmagnesium bromide / diethyl ether

2: 85 percent / pyridinium hydrochloride / 220 °C

With ethylmagnesium bromide; pyridine hydrochloride; In diethyl ether;

DOI:10.1021/jm00142a014

upstream raw materials:

5,6-di-(3'-methoxyphenyl)-decane

1-(3'-methoxyphenyl)-pentan-1-ol

1-chlor-1-(3'-methoxyphenyl)-pentane

3-methoxy-benzaldehyde

Refernces

• 1、 -. "Novel di-(3'-hydroxyphenyl)-alkane compounds, process of preparation and their use in medicine". . . Retrieved 2008/06/13.