1-CHLORO-1-METHYLSILACYCLOBUTANE

Base Information

• Chemical Name: 1-CHLORO-1-METHYLSILACYCLOBUTANE
• CAS No.: 2351-34-0
• Molecular Formula: C4H9 Cl Si
• Molecular Weight: 120.654
• Mol file: 2351-34-0.mol

Synonyms:1-Chloro-1-methyl-1-silacyclobutane;1-Chloro-1-methylsilacyclobutane; 1-Methyl-1-chloro-1-silacyclobutane;1-Methyl-1-chlorosilacyclobutane

Chemical Property of 1-CHLORO-1-METHYLSILACYCLOBUTANE

Chemical Property:

• Vapor Pressure: 44mmHg at 25°C
• Refractive Index: n20/D 1.45(lit.)
• Boiling Point: 99.4°Cat760mmHg
• Flash Point: 2.6°C
• PSA: 0.00000
• Density: 0.98g/cm³
• LogP: 2.20420
• Solubility.: soluble in most aprotic organic solvents.

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-Chloro-1-methylsilacyclobutane 98% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F,C
• Statements: 11-14-34
• Safety Statements: 16-26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Physical properties: bp 103°C; d 0.985 g cm?3.
• Uses: Siletanes (silacyclobutanes) represent a unique class of silicon-based reagents that have enjoyed much success in a number of synthetic applications including aldol reactions, allylations, cross-coupling reactions, carbosilane oxidations, and ring expansions. The manifestation of their strain in enhanced Lewis acidity and in the ring opening to silanols accounts for their utility. 1-Chloro-1-methylsiletane can be used for the preparation of the various siletane derivatives for these applications.Grignard reagents react efficiently with 1-chloro-1-methylsiletane to provide the corresponding aryl-, alkenyl-, or alkylsiletanes (eqs 1–3).On the contrary, reactions with alkyllithiums are limited to the reaction of 1 with a lithium acetylide (eq 4).The reaction of 1 with an intermediate vinylalane obtained by hydroalumination of 1-heptyne gave (E)-1-heptenylmethylsiletane in >99/1 isomeric purity (eq 5).The reaction of 1 with LiAlD4 afforded 1-deuterio-1-methylsiletane (eq 6). Intermediate in the formation of enoxysilacyclobutanes.

Technology Process of 1-CHLORO-1-METHYLSILACYCLOBUTANE

There total 6 articles about 1-CHLORO-1-METHYLSILACYCLOBUTANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

dichloro(3-chloropropyl)methylsilane (7787-93-1) → 1-chloro-1-methylsiletane (2351-34-0)

Guidance literature:

With magnesium; In diethyl ether; for 48h;

DOI:10.1016/S0022-328X(00)83695-5

Reference yield: 64.0%

(3-chloropropyl)dichloromethylsilane + 1,1-Dibromoethane (557-91-5) → 1-chloro-1-methylsiletane (2351-34-0)

Guidance literature:

With magnesium; In tetrahydrofuran;

Reference yield: 55.0%

Methyltrichlorosilane (75-79-6) + 1.3-chlorobromopropane (109-70-6) → 1-chloro-1-methylsiletane (2351-34-0)

Guidance literature:

With magnesium; ethylene dibromide; In dibutyl diglyme; at 20 - 95 ℃; for 2h;

upstream raw materials:

dichloro(3-chloropropyl)methylsilane

2,3-dimethyl-buta-1,3-diene

Methyltrichlorosilane

1.3-chlorobromopropane

Downstream raw materials:

bistrimethyl(4,4'-biphenoxy)silane

1-Methyl-1-(4-trimethylsilanyloxy-phenyl)-siletane

1,10-decanediol bis(trimethylsilyl ether)

hexane-1,6-diol bis(trimethylsilyl) ether

Refernces

• 1、 Nametkin et al.. "-". . . Retrieved 1973.
• 2、 Matsumoto, Kozo,Hasegawa, Hirohiko,Matsuoka, Hideki. "Synthesis of sodium-polystyrenesulfonate-grafted nanoparticles by core-cross-linking of block copolymer micelles". . p. 7197 - 7204. Retrieved 2004.
• 3、 -. "SYNTHETIC PROCESS FOR CYCLIC ORGANOSILANES". Page/Page column 8-9. . Retrieved 2008/06/13.