Methyl 2-amino-4-(methylthio)butanoate hydrochloride

Base Information

• Chemical Name: Methyl 2-amino-4-(methylthio)butanoate hydrochloride
• CAS No.: 16118-36-8
• Molecular Formula: C6H13NO2S.ClH
• Molecular Weight: 199.702
• Hs Code.: 2930909090
• European Community (EC) Number: 240-285-0
• DSSTox Substance ID: DTXSID90936465
• NSC Number: 522231
• Mol file: 16118-36-8.mol

Synonyms:16118-36-8;methyl 2-amino-4-(methylthio)butanoate hydrochloride;H-DL-Met-Ome HCl;H-Met-Ome HCl;Methyl DL-methionate HCl;Methyl DL-methionate hydrochloride;EINECS 240-285-0;Methionine, methyl ester, hydrochloride (1:1);methyl 2-azanyl-4-methylsulfanyl-butanoate hydrochloride;dl-methionine methyl ester hydrochloride;2-amino-4-(methylthio)butanoic acid methyl ester hydrochloride;MFCD00070385;DL-Met-OMe??HCl;H-DL-Met-OMe.HCl;H-D-Met-OMe inverted exclamation mark currencyHCl;(s)-methyl 2-amino-4-(methylthio)butanoate hydrochloride;H-DL-Met-Ome hydrochloride;SCHEMBL200898;methyl 2-amino-4-methylsulfanylbutanoate;hydrochloride;methyl 2-amino-4-(methylsulfanyl)butanoate hydrochloride;Methyl methioninate hydrochloride;DTXSID90936465;Methyl DL-methioninate hydrochloride;MFCD00067540;NSC522231;AKOS008965667;NSC-522231;l-methionine methyl ester hydro-chloride;AS-12214;Methionine,methylester,hydrochloride(1:1);SY017688;SY066424;Methyl 2-amino-4-(methylthio)butanoate HCl;CS-0169307;FT-0625548;FT-0627956;FT-0702868;EN300-09315;Methyl methioninate--hydrogen chloride (1/1);F10668;A817542;A836576

Chemical Property of Methyl 2-amino-4-(methylthio)butanoate hydrochloride

Chemical Property:

• Vapor Pressure: 0.0388mmHg at 25°C
• Boiling Point: 277.6 °C at 760 mmHg
• Flash Point: 121.7 °C
• PSA: 77.62000
• LogP: 1.74210
• Storage Temp.: −20°C
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 199.0433776
• Heavy Atom Count: 11
• Complexity: 108

Purity/Quality:

99% ^*data from raw suppliers

DL-methionine methyl ester hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(=O)C(CCSC)N.Cl

Technology Process of Methyl 2-amino-4-(methylthio)butanoate hydrochloride

There total 2 articles about Methyl 2-amino-4-(methylthio)butanoate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + DL-methionine (59-51-8,26062-47-5,58576-49-1) → methionine methyl ester hydrochloride (16118-36-8)

Guidance literature:

With hydrogenchloride;

Reference yield:

DL-methionine methyl ester (10332-17-9,874219-77-9) → methionine methyl ester hydrochloride (16118-36-8)

Guidance literature:

With hydrogenchloride; In water;

DOI:10.1016/j.tetasy.2010.08.010

Reference yield: 97.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + methionine methyl ester hydrochloride (16118-36-8) + phenylacetylene (536-74-3) → methyl 2-(bis(3-phenylprop-2-yn-1-yl)amino)-4-(methylthio)butanoate

Guidance literature:

With sodium hydrogencarbonate; copper(l) chloride; In water; at 35 ℃; for 18h; Inert atmosphere;

DOI:10.1021/ol301017q

upstream raw materials:

methanol

DL-methionine

DL-methionine methyl ester

Downstream raw materials:

N-[N-(4-methoxy-benzyloxycarbonyl)-methionyl]-glycine

N-cinnamoyl-L-methionine methyl ester

(R)-α-methylbenzylcarbamoyl-DL-methionine methyl ester

Boc-Phe-Met-OMe

Refernces

• 1、 -. "Methionine derivate corrosion inhibitor for steel pickling and compounding method thereof". Paragraph 0010; 0024; 0028-0029. . Retrieved 2018/04/01.
• 2、 Quigley, Cormac,Rodriguez-Docampo, Zaida,Connon, Stephen J.. "Highly tunable arylated cinchona alkaloids as bifunctional catalysts". supporting information; scheme or table. p. 1443 - 1445. Retrieved 2012/03/11.