Benzylidene dibenzoylmethane

Base Information

• Chemical Name: Benzylidene dibenzoylmethane
• CAS No.: 5398-64-1
• Molecular Formula: C22H16 O2
• Molecular Weight: 312.368
• Mol file: 5398-64-1.mol

Synonyms:1,3-Propanedione,2-benzylidene-1,3-diphenyl- (8CI);2-(Benzylidene)-1,3-diphenyl-1,3-propanedione; Benzylidene dibenzoylmethane;NSC 4529; NSC 638188; a-Benzoylchalcone

Chemical Property of Benzylidene dibenzoylmethane

Chemical Property:

• Vapor Pressure: 1.19E-09mmHg at 25°C
• Melting Point: 87-88 °C
• Boiling Point: 487.4°Cat760mmHg
• Flash Point: 180.6°C
• Density: 1.176g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzylidene dibenzoylmethane

There total 7 articles about Benzylidene dibenzoylmethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

benzaldehyde (100-52-7) + 1,3-diphenylpropanedione (120-46-7,61346-73-4) → 2-benzylidene-1,3-diphenylpropane-1,3-dione (5398-64-1)

Guidance literature:

With piperidine; acetic acid; In benzene; for 2h; Heating;

DOI:10.1016/S0040-4020(01)01173-5

Reference yield: 72.0%

2-phenyl-4,4,6-trimethyltetrahydro-(2H)-1,3-oxazine (31771-33-2) + 1,3-diphenylpropanedione (120-46-7,61346-73-4) → 2-benzylidene-1,3-diphenylpropane-1,3-dione (5398-64-1)

Guidance literature:

With acetic acid; In acetonitrile; for 40h; Heating;

DOI:10.1016/0040-4020(96)00879-4

Reference yield:

(Z)-3-Hydroxy-2-(morpholin-4-yl-phenyl-methyl)-1,3-diphenyl-propenone → morpholine (110-91-8,99108-56-2) + 2-benzylidene-1,3-diphenylpropane-1,3-dione (5398-64-1)

Guidance literature:

With potassium chloride; In water; dimethyl sulfoxide; at 20 ℃; Rate constant; Equilibrium constant;

upstream raw materials:

benzaldehyde

1,3-diphenylpropanedione

benzoic acid

2-phenyl-4,4,6-trimethyltetrahydro-(2H)-1,3-oxazine

Downstream raw materials:

3-Benzoyl-4-oxo-2,4-diphenylbutanenitrile

benzoyl-1 (diphenyl-1,3 oxo-3 propyl)-2 hydrazine

C₃₄H₄₄O₂P⁽¹⁺⁾*Cl^(1-)

(5-(4-chlorophenyl)-2,4-diphenylfuran-3-yl)(phenyl)methanone

Refernces

• 1、 Liu, Ye,Mao, Yujian,Hu, Yanwei,Gui, Jingjing,Wang, Liang,Wang, Wei,Zhang, Shilei. "The Employment of Sodium Hydride as a Michael Donor in Palladium-catalyzed Reductions of α, β-Unsaturated Carbonyl Compounds". supporting information. p. 1554 - 1558. Retrieved 2019/02/16.
• 2、 Saravanakumar, Rajendran,Markopoulos, Georgios,Bahrin, LucianGabriel,Jones, PeterG.,Hopf, Henning. "The Regiospecific Preparation of 2-Substituted Tribenzotriquinacenes". . p. 453 - 456. Retrieved 2013/04/10.