PROPARGYL BENZOATE 98

Base Information

• Chemical Name: PROPARGYL BENZOATE 98
• CAS No.: 6750-04-5
• Molecular Formula: C10H8 O2
• Molecular Weight: 160.172
• Mol file: 6750-04-5.mol

Synonyms:2-Propyn-1-ol,benzoate (7CI,8CI,9CI); 2-Propynyl benzoate; Benzoic acid 2-propynyl ester;Benzoic acid propargyl ester; NSC 349955; Propargyl benzoate

Chemical Property of PROPARGYL BENZOATE 98

Chemical Property:

• Vapor Pressure: 0.0113mmHg at 25°C
• Refractive Index: n20/D 1.5320(lit.)
• Boiling Point: 225-226 °C(lit.)
• Flash Point: >230 °F
• PSA: 26.30000
• Density: 1.106 g/mL at 25 °C(lit.)
• LogP: 1.47660
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

Propargyl benzoate 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: Propargyl benzoate may be used in the preparation of amphiphilic graft copolymers of poly(ε-caprolactone) (PCL).

Technology Process of PROPARGYL BENZOATE 98

There total 24 articles about PROPARGYL BENZOATE 98 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

benzoyl chloride (98-88-4) + propargyl alcohol (107-19-7) → propargyl benzoate (6750-04-5)

Guidance literature:

benzoyl chloride; propargyl alcohol; In dichloromethane; at 20 ℃;

With poly{trans-bicyclo[2.2.1]hept-5-ene-2,3-di(chlorocarbonyl)}; In dichloromethane; Heating;

DOI:10.1021/ol0352759

Reference yield: 97.0%

propargyl alcohol (107-19-7) + benzoic acid (65-85-0,8013-63-6) → propargyl benzoate (6750-04-5)

Guidance literature:

With graphene oxide; In 1,2-dichloro-ethane; at 100 ℃; for 24h;

DOI:10.1055/s-0036-1588399

Reference yield: 95.0%

propargyl alcohol (107-19-7) + benzoic acid anhydride (93-97-0) → propargyl benzoate (6750-04-5)

Guidance literature:

propargyl alcohol; benzoic acid anhydride; With triethylamine; In dichloromethane; at 0 ℃; for 0.25h; under 760.051 Torr;

With dmap; In dichloromethane; at 0 - 20 ℃; for 4h; under 760.051 Torr;

DOI:10.1002/adsc.201900314

upstream raw materials:

benzoyl chloride

propargyl alcohol

1-Benzoyl-4-jodpyrazol

benzoic acid

Downstream raw materials:

4-N-dimethylaminobutyn-2-yl ester of benzoic acid

3-benzoyloxy-1-iodo-1-propyne

4-Methylenepyrazolebenzoate

Benzoic acid 4-dioctylamino-but-2-ynyl ester

Refernces

• 1、 Ming, Xiao-Xia,Wu, Shuai,Tian, Ze-Yu,Song, Jia-Wei,Zhang, Cheng-Pan. "Pd/Cu-Catalyzed Vinylation of Terminal Alkynes with (2-Bromoethyl)diphenylsulfonium Triflate". supporting information. p. 6795 - 6800. Retrieved 2021/09/08.
• 2、 Bai, Xue-Qian,Cao, Li-Ting,Li, Chun-Shi,Sun, Si-Mei,Zhang, Tian-Yi,Zhao, Dong-Hai. "New ursolic acid derivatives bearing 1,2,3-triazole moieties: design, synthesis and anti-inflammatory activity in vitro and in vivo". . . Retrieved 2021/06/07.