(4-Bromophenyl)hydrazine

Base Information

• Chemical Name: (4-Bromophenyl)hydrazine
• CAS No.: 589-21-9
• Molecular Formula: C6H7BrN2
• Molecular Weight: 187.039
• Hs Code.: 2928000090
• European Community (EC) Number: 209-640-7
• NSC Number: 190724
• UNII: 1D906VQ17M
• DSSTox Substance ID: DTXSID80207631
• Nikkaji Number: J94.986H
• Wikidata: Q27252272
• Mol file: 589-21-9.mol

Synonyms:(4-Bromophenyl)hydrazine;589-21-9;4-Bromophenylhydrazine;p-Bromophenylhydrazine;Hydrazine, (4-bromophenyl)-;(p-Bromophenyl)hydrazine;(4-Bromo-phenyl)-hydrazine;Hydrazine, (p-bromophenyl)-;MFCD01935685;1-(4-Bromophenyl)hydrazine;UNII-1D906VQ17M;1D906VQ17M;EINECS 209-640-7;NSC-190724;p-bromophenyl hydrazine;p-Bromphenylhydrazin;(4-bromophenyl)diazane;4-bromophenyl hydrazine;N(N)c1ccc(Br)cc1;4-bromo-phenyl hydrazine;(4-bromophenyl)-Hydrazine;SCHEMBL7151;TimTec1_005956;Hydrazine,(4-bromophenyl)-;1-(4-Bromophenyl)hydrazine #;Hydrazine, 1-(p-bromophenyl)-;DTXSID80207631;HMS1550O16;P-BROMOPHENYLHYDRAZINE [MI];BBL009630;NSC190724;STK697361;AKOS000312970;NSC 190724;PS-3070;NCGC00173351-01;SY101512;BB 0249756;CS-0060253;FT-0617693;W16688;2-IODOTETRAFLUOROETHYLTRIFLUOROMETHYLETHER;A832075;Q27252272

Chemical Property of (4-Bromophenyl)hydrazine

Chemical Property:

• Vapor Pressure: 0.00278mmHg at 25°C
• Melting Point: 102-104 °C
• Refractive Index: 1.68
• Boiling Point: 285.6 °C at 760 mmHg
• PKA: 4.93±0.20(Predicted)
• Flash Point: 126.5 °C
• PSA: 38.05000
• Density: 1.666 g/cm³
• LogP: 2.50800
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 185.97926
• Heavy Atom Count: 9
• Complexity: 79.1

Purity/Quality:

99% ^*data from raw suppliers

(4-Bromophenyl)hydrazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1NN)Br
• Uses: In preparation of indoleacetic acid derivatives; in the study of transosazonation of sugar phenylosazones.

Technology Process of (4-Bromophenyl)hydrazine

There total 29 articles about (4-Bromophenyl)hydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

N-(4-bromophenyl)-nitramine (412328-47-3) → (4-bromophenyl)hydrazine (589-21-9)

Guidance literature:

With hydrogenchloride; tin(ll) chloride; In water; for 4h; Cooling with ice;

DOI:10.1016/j.tet.2013.11.084

Reference yield: 71.0%

4-bromobenzenediazonium tetrafluoroborate (673-40-5) → (4-bromophenyl)hydrazine (589-21-9)

Guidance literature:

With nickel dichloride; zinc; In tetrahydrofuran;

DOI:10.1039/a905588f

Reference yield:

4-bromophenylhydrazine hydrochloride (622-88-8,41931-18-4) → (4-bromophenyl)hydrazine (589-21-9)

Guidance literature:

With sodium carbonate; In dichloromethane; water;

upstream raw materials:

acetone p-bromophenylhydrazone

acetone phenylhydrazone

(4-bromophenyl)diazonium chloride

phenylhydrazine

Downstream raw materials:

1,5-bis-(4-bromo-phenyl)-formazan

5-nitro-thiophene-2-carbaldehyde-(4-bromo-phenylhydrazone)

2-acetyl-1-(4-bromophenyl)hydrazine

2-(4-bromo-phenyl)-5-methyl-1,2-dihydro-pyrazol-3-one

Refernces

• 1、 Dey, Raghunath,Kumar, Pankaj,Banerjee, Prabal. "Lewis Acid Catalyzed Annulation of Cyclopropane Carbaldehydes and Aryl Hydrazines: Construction of Tetrahydropyridazines and Application Toward a One-Pot Synthesis of Hexahydropyrrolo[1,2- b]pyridazines". . p. 5438 - 5449. Retrieved 2018/05/28.
• 2、 Mane, Yogesh D.,Sarnikar, Yuvaraj P.,Surwase, Santosh M.,Biradar, Dhanraj O.,Gorepatil, Pratapsinha B.,Shinde, Vishnu S.,Khade, Bhimrao C.. "Design, synthesis, and antimicrobial activity of novel 5-substituted indole-2-carboxamide derivatives". . p. 1253 - 1275. Retrieved 2017/02/10.