Cyclopentanecarboxylic acid, 1-methyl-, methyl ester

Base Information

• Chemical Name: Cyclopentanecarboxylic acid, 1-methyl-, methyl ester
• CAS No.: 4630-83-5
• Molecular Formula: C8H14O2
• Molecular Weight: 142.198
• DSSTox Substance ID: DTXSID10196807
• Wikidata: Q83069816
• Mol file: 4630-83-5.mol

Synonyms:methyl 1-methylcyclopentanecarboxylate;4630-83-5;methyl 1-methylcyclopentane-1-carboxylate;Cyclopentanecarboxylic acid, 1-methyl-, methyl ester;Cyclopentanoic acid, 1-methyl, methyl ester;SCHEMBL17958;DTXSID10196807;methyl1-methylcyclopentanecarboxylate;MFCD22374940;1-Methyl methylcyclopentanecarboxylate;AKOS015997877;CS-0089153;1-methyl-cyclopentanecarboxylic acid methyl ester

Chemical Property of Cyclopentanecarboxylic acid, 1-methyl-, methyl ester

Chemical Property:

• Vapor Pressure: 2.19mmHg at 25°C
• Refractive Index: 1.4630 (estimate)
• Boiling Point: 162.2°Cat760mmHg
• Flash Point: 48.1°C
• PSA: 26.30000
• Density: 0.982g/cm³
• LogP: 1.73970
• XLogP3: 2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 142.099379685
• Heavy Atom Count: 10
• Complexity: 134

Purity/Quality:

95% ^*data from raw suppliers

Methyl 1-methylcyclopentanecarboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1(CCCC1)C(=O)OC

Technology Process of Cyclopentanecarboxylic acid, 1-methyl-, methyl ester

There total 7 articles about Cyclopentanecarboxylic acid, 1-methyl-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C14H17NO4S → methyl cyclohexylcarboxylate (4630-82-4) + methyl 1-methylcyclopentanecarboxylate (4630-83-5)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene; at 80 ℃; for 1h; Kinetics; Irradiation;

DOI:10.1021/ol990557n

Reference yield:

cyclohexene (110-83-8) → methyl cyclohexylcarboxylate (4630-82-4) + methyl 1-methylcyclopentanecarboxylate (4630-83-5)

Guidance literature:

With sulfuric acid; under 58840.6 Torr; anschliessend mit Methanol behandeln;

Reference yield:

methanol (67-56-1) + cyclohexene (110-83-8) → methyl cyclohexylcarboxylate (4630-82-4) + methyl 1-methylcyclopentanecarboxylate (4630-83-5)

Guidance literature:

With sulfuric acid; under 58840.6 Torr;

upstream raw materials:

methanol

2-chloro-1-cyclopentylethan-1-one

sodium methylate

sulfuric acid

Downstream raw materials:

1-methylcyclopentanecarbonyl chloride

(3R,4R,5S,6R)-2-(4-chloro-3-(4-((1-methylcyclopentyl)methoxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

(3R,4S,5S,6R)-2-(4-chloro-3-(4-((1-methylcyclopentyl)methoxy)benzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol

4-bromo-1-chloro-2-(4-((1-methylcyclopentyl)methoxy)benzyl)benzene

Refernces

• 1、 Della, Ernest W.,Kostakis, Chris,Smith, Paul A.. "Regioselective 6-endo cyclization of 5-carbomethoxy-5-hexenyl radicals: A convenient synthesis of derivatives of the 1-azabicyclo[2.2.1]heptyl system". . p. 363 - 365. Retrieved 2008/02/13.