2-Aminoethanesulfonamide hydrochloride

Base Information

• Chemical Name: 2-Aminoethanesulfonamide hydrochloride
• CAS No.: 89756-60-5
• Molecular Formula: C2H9ClN2O2S
• Molecular Weight: 160.625
• Hs Code.: 2935009090
• European Community (EC) Number: 289-519-3
• DSSTox Substance ID: DTXSID20237871
• Mol file: 89756-60-5.mol

Synonyms:2-aminoethanesulfonamide hydrochloride;89756-60-5;2-Aminoethanesulphonamide monohydrochloride;2-Aminoethanesulfonamide HCl;2-Aminoethanesulfonamide, HCl;Ethanesulfonamide, 2-amino-, monohydrochloride;2-aminoethanesulfonamide;hydrochloride;2-aminoethane-1-sulfonamide hydrochloride;2-Aminoethanesulphonamide HCl;EINECS 289-519-3;MFCD02258341;2-Amino-ethanesulfonamide hydrochloride;C2H9ClN2O2S;C2H8N2O2S.ClH;SCHEMBL345080;DTXSID20237871;DGUVEYAZTOUCEJ-UHFFFAOYSA-N;C2-H8-N2-O2-S.Cl-H;2-aminoethanesulfonamidehydrochloride;2-aminoethylsulphonamide hydrochloride;2-azanylethanesulfonamide hydrochloride;AKOS015848165;SB39698;2-aminoethane sulphonamide hydrochloride;2-aminoethanesulfonamide hydrochloric acid;AS-19244;SY029832;2-amino-ethanesulfonic acid amide HCl salt;2-aminoethane-1-sulphonamide hydrochloride;CS-0158306;FT-0653166;2-Aminoethanesulfonamide hydrochloride (1:1);2-aminoethanesulfonic acid amide hydrochloride;EN300-36065;2-amino-ethanesulfonic acid amide hydrochloride;A843299;F8881-5834;Z432066942

Chemical Property of 2-Aminoethanesulfonamide hydrochloride

Chemical Property:

• Vapor Pressure: 0.000917mmHg at 25°C
• Melting Point: 133 °C
• Boiling Point: 303.7 °C at 760 mmHg
• Flash Point: 137.5 °C
• PSA: 94.56000
• LogP: 1.51700
• Storage Temp.: Sealed in dry,Room Temperature
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 160.0073264
• Heavy Atom Count: 8
• Complexity: 121

Purity/Quality:

99% ^*data from raw suppliers

TaurinamideHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CS(=O)(=O)N)N.Cl
• Uses: Taurinamide is a derivative of Taurolidine; a drug with antimicrobial and antiendotoxic properties.

Technology Process of 2-Aminoethanesulfonamide hydrochloride

There total 8 articles about 2-Aminoethanesulfonamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.3%

2-bromoethanesulfonyl chloride (54429-56-0) → taurinamide hydrochloride (89756-60-5)

Guidance literature:

2-bromoethanesulfonyl chloride; With ammonia; In tetrahydrofuran; for 3h; under 760.051 Torr; Cooling with ice;

With hydrogenchloride; In ethanol; at 20 - 25 ℃; for 0.5h; Time;

Reference yield: 92.2%

N-carbobenzoxy-β-aminoethanesulfonamide (136027-17-3) → taurinamide hydrochloride (89756-60-5)

Guidance literature:

With hydrogenchloride; In water; for 1h; Reflux;

Reference yield: 91.84%

C18H12N2O6S → taurinamide hydrochloride (89756-60-5)

Guidance literature:

C₁₈H₁₂N₂O₆S; With sodium tetrahydroborate; In ethanol; at 50 ℃; for 4h;

With hydrogenchloride; In ethanol; water; pH=2 - 3; Temperature; Cooling with ice;

upstream raw materials:

2-phthalimidoethane sulfonamide

2-formamidoethylsulfonamide

17-(pyrimidin-5-yl)oestra-1,3,5⁽¹⁰⁾,16-tetraene-3-carboxylic acid

17-(pyridin-3-yl)estra-1,3,5⁽¹⁰⁾,16-tetraene-3-carboxylic acid

Downstream raw materials:

N-(2-sulfamoylethyl)benzamide

Refernces

• 1、 -. "Method for synthesis of taurideamide hydrochloride (2-aminoethylsulfonamide hydrochloride)". Paragraph 0032; 0057. . Retrieved 2018/04/02.
• 2、 Mujumdar, Prashant,Teruya, Kanae,Tonissen, Kathryn F.,Vullo, Daniela,Supuran, Claudiu T.,Peat, Thomas S.,Poulsen, Sally-Ann. "An Unusual Natural Product Primary Sulfonamide: Synthesis, Carbonic Anhydrase Inhibition, and Protein X-ray Structures of Psammaplin C". supporting information. p. 5462 - 5470. Retrieved 2016/07/06.