Ethyldiphenylphosphine

Base Information

• Chemical Name: Ethyldiphenylphosphine
• CAS No.: 607-01-2
• Molecular Formula: C14H15P
• Molecular Weight: 214.247
• Hs Code.: 29310099
• European Community (EC) Number: 627-386-9
• NSC Number: 151254
• DSSTox Substance ID: DTXSID4073207
• Nikkaji Number: J136.480D
• Wikidata: Q72473199
• Mol file: 607-01-2.mol

Synonyms:Ethyldiphenylphosphine;607-01-2;Phosphine, ethyldiphenyl-;ethyl(diphenyl)phosphane;diphenylphosphinoethane;C14H15P;MFCD00015170;Diphenyl ethyl phosphine;ethyldiphenylphosphane;diphenylphosphinoethan;NSC151254;Ethyl(diphenyl)phosphine;Ethyldiphenylphosphine, 98%;P(CC)(c1ccccc1)c2ccccc2;SCHEMBL34614;DTXSID4073207;3-(4-Hexylbenzoyl)-propionicacid;AMY11733;C14-H15-P;AKOS015839008;CS-W014931;NSC 151254;NSC-151254;SC11148;AS-57678;SY048817;LS-105963;E0519;FT-0625261;F10252;A868910;DIPHENYLETHYLPHOSPHINE;ETHYLDIPHENYLPHOSPHINE

Chemical Property of Ethyldiphenylphosphine

Chemical Property:

• Appearance/Colour: Clear colorless liquid
• Vapor Pressure: 0.00231mmHg at 25°C
• Refractive Index: n20/D 1.614(lit.)
• Boiling Point: 298 °C at 760 mmHg
• Flash Point: 139.6 °C
• PSA: 13.59000
• Density: 1.048 g/mL at 25 °C(lit.)
• LogP: 3.13920
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Sensitive.: Air Sensitive
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 3
• Exact Mass: 214.091137476
• Heavy Atom Count: 15
• Complexity: 148

Purity/Quality:

98% ^*data from raw suppliers

Ethyldiphenylphosphine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCP(C1=CC=CC=C1)C2=CC=CC=C2
• Uses: Catalyst for:Three component coupling reactions of arylaldehydes with Me vinyl ketone and phthalimideRegio- and stereoselective hydroalkynylation of methylenecyclopropanesSynthesis of oxazolidines, thiazolidines, pyrrolidines, and indolesDimer to monomer conversionTandem Morita-Baylis-Hillman/Michael addition reactionsPlatinum-catalyzed cyclizationRegioselective and stereoselective [3+2] cycloadditionPlatinum-catalyzed intermolecular hydroaminationHydroformylation reactions

Technology Process of Ethyldiphenylphosphine

There total 27 articles about Ethyldiphenylphosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

1,3-dioxoisoindolin-2-yl propionate + chloro-diphenylphosphine (1079-66-9,74391-44-9) → ethyl-diphenyl-phosphane (607-01-2)

Guidance literature:

With N,N,N',N'',N'''-pentamethyldiethylenetriamine; zinc; In N,N-dimethyl-formamide; at 20 ℃; for 12h;

DOI:10.1021/acscatal.9b03366

Reference yield: 96.0%

ethydiphenylphosphine oxide (1733-57-9) → ethyl-diphenyl-phosphane (607-01-2)

Guidance literature:

With aluminium hydride*tetrahydrofuran; 1,1'-sulfinylbisbenzene; In tetrahydrofuran; for 0.5h; Heating;

DOI:10.1016/S0040-4039(99)00998-3

Reference yield: 83.0%

ethyl bromide (74-96-4) + diphenylphosphane (829-85-6) → ethyl-diphenyl-phosphane (607-01-2)

Guidance literature:

With cesium hydroxide; 4 Angstroem MS; In N,N-dimethyl-formamide; at 23 ℃; for 24h;

DOI:10.1016/j.tetlet.2003.09.117

upstream raw materials:

ethylmagnesium bromide

chloro-diphenylphosphine

diethylzinc

ethyldiphenylphosphine N-phenylimide

Downstream raw materials:

(+/-)-2-(ethylphenylphosphino)pyridine

C₂₆H₂₅NO₃P₂

cyclohexyldiphenylphosphine

diphenyl(methyl)phosphine

Refernces

• 1、 Pearce, Kyle G.,Borys, Andryj M.,Clark, Ewan R.,Shepherd, Helena J.. "Exploring the Reactivity of Donor-Stabilized Phosphenium Cations: Lewis Acid-Catalyzed Reduction of Chlorophosphanes by Silanes". supporting information. p. 11530 - 11536. Retrieved 2018/09/21.
• 2、 Kuroboshi, Manabu,Kita, Toshihito,Aono, Asuka,Katagiri, Toshimasa,Kikuchi, Seiya,Yamane, Syoko,Kawakubo, Hiromu,Tanaka, Hideo. "Reduction of phosphine oxides to the corresponding phosphine derivatives in Mg/Me3SiCl/DMI system". . p. 918 - 920. Retrieved 2015/02/05.