Rutaecarpine

Base Information Edit

Chemical Name:Rutaecarpine
CAS No.:84-26-4
Molecular Formula:C18H13N3O
Molecular Weight:287.321
Hs Code.:29339900
European Community (EC) Number:635-907-6
NSC Number:258317
UNII:8XZV289PRY
DSSTox Substance ID:DTXSID00232884
Nikkaji Number:J4.894A,J3.210.250F
Wikipedia:Rutecarpine
Wikidata:Q15424771
Pharos Ligand ID:A88HY4UARGB1
Metabolomics Workbench ID:49692
ChEMBL ID:CHEMBL85139
Mol file:84-26-4.mol

Synonyms:8,13-dihydroindolo(2',3':3,4)pyrido(2,1-b)quinazolin-5(7H)-one;rutaecarpine;rutecarpine

Suppliers and Price of Rutaecarpine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Rutaecarpine
20mg
$ 320.00

TRC
Rutaecarpine
100mg
$ 70.00

TCI Chemical
Rutaecarpine >98.0%(HPLC)(N)
200mg
$ 166.00

Sigma-Aldrich
Rutaecarpine >98% (HPLC)
5mg
$ 130.00

Sigma-Aldrich
Rutaecarpine >98% (HPLC)
25mg
$ 512.00

Medical Isotopes, Inc.
Rutaecarpine
1 g
$ 1380.00

Medical Isotopes, Inc.
Rutaecarpine
100 mg
$ 610.00

Matrix Scientific
8,13-Dihydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one
0.500g
$ 120.00

Matrix Scientific
8,13-Dihydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one
1g
$ 150.00

Matrix Scientific
8,13-Dihydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one
5g
$ 460.00

Total 119 raw suppliers

Chemical Property of Rutaecarpine Edit

Chemical Property:

Appearance/Colour:white solid
Vapor Pressure:0mmHg at 25°C
Melting Point:259.5 - 260oC
Refractive Index:1.781
Boiling Point:550.072 °C at 760 mmHg
PKA:15.79±0.20(Predicted)
Flash Point:286.473 °C
PSA：50.68000
Density:1.456 g/cm³
LogP:3.10090
Storage Temp.:2-8°C
Solubility.:DMSO: 18 mg/mL clear yellow solution, soluble
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:287.105862047
Heavy Atom Count:22
Complexity:517

Purity/Quality:

99% ^*data from raw suppliers

Rutaecarpine ^*data from reagent suppliers

Safty Information:

Pictogram(s): T
Hazard Codes:T
Statements: 25-36/37/38
Safety Statements: 45-36-26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN2C(=NC3=CC=CC=C3C2=O)C4=C1C5=CC=CC=C5N4
Description This alkaloid occurs with Evodiamine (q.v.) in the Chinese drug 'Wou-chou-yu' which is the dried fruit of Evodia rutaecarpa Benth. It crystallizes from boiling EtOH as colourless, or pale yellow, needles and is optically inactive. The acetyl derivative has m.p. 184-6°C and the benzoyl compound, m.p. 194°C. The alkaloid gives a yellow colour with concentrated H2S04 and is decomposed by KOH in boiling amyl alcohol yielding anthranilic acid and 3-{3-aminoethylindole- 2-O!carboxylic acid, CllH120 2N2, silky crystals, m.p. 257°C. Pharmacologically, the alkaloid causes increased arterial pressure on injection.
Uses Rutaecarpine is an indole alkaloid contained in the fruit of Evodiae fruits. It been shown to ameliorate bodyweight gain through orexigenic neuropeptides NPY and AgRP. It also playes a role in the treatment of high blood pressure

Technology Process of Rutaecarpine

There total 130 articles about Rutaecarpine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%