2-Ethyl-3,5-dimethylpyridine

Base Information

• Chemical Name: 2-Ethyl-3,5-dimethylpyridine
• CAS No.: 1123-96-2
• Molecular Formula: C9H13N
• Molecular Weight: 135.209
• Hs Code.: 2933399090
• European Community (EC) Number: 214-383-9
• UNII: 06CS7VYH7Y
• DSSTox Substance ID: DTXSID30149991
• Nikkaji Number: J203.359C
• Wikidata: Q27236199
• Mol file: 1123-96-2.mol

Synonyms:2-Ethyl-3,5-dimethylpyridine;1123-96-2;Parvoline;3,5-Dimethyl-2-ethylpyridine;2-ethyl-3,5-dimethyl-pyridine;Pyridine, 2-ethyl-3,5-dimethyl-;EINECS 214-383-9;UNII-06CS7VYH7Y;06CS7VYH7Y;3,5-Lutidine, 2-ethyl-;Pyridine,2-ethyl-3,5-dimethyl-;.alpha.-Parvoline;SCHEMBL873234;DTXSID30149991;MFCD00051049;AKOS006273527;SB54933;BS-51715;CS-0321319;FT-0649409;E77044;A936849;Q27236199

Chemical Property of 2-Ethyl-3,5-dimethylpyridine

Chemical Property:

• Vapor Pressure: 0.454mmHg at 25°C
• Melting Point: 31.33°C (estimate)
• Refractive Index: 1.5
• Boiling Point: 200.7 °C at 760 mmHg
• Flash Point: 64.5 °C
• PSA: 12.89000
• Density: 0.913 g/cm³
• LogP: 2.26080
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 135.104799419
• Heavy Atom Count: 10
• Complexity: 101

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Ethyl-3,5-dimethylpyridine 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC1=C(C=C(C=N1)C)C

Technology Process of 2-Ethyl-3,5-dimethylpyridine

There total 34 articles about 2-Ethyl-3,5-dimethylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

N-(2-methylpent-2-en-1-ylidene)cyclopropanamine (1174400-14-6) → 2-ethyl-3,5-dimethylpyridine (1123-96-2)

Guidance literature:

With palladium dichloride; at 170 ℃; for 3h;

DOI:10.1134/S1070428008120208

Reference yield: 99.0%

N-(2-methylpent-2-en-1-ylidene)prop-2-en-1-amine (3298-39-3) → 2-ethyl-3,5-dimethylpyridine (1123-96-2)

Guidance literature:

With palladium dichloride; at 160 ℃; for 4h; Autoclave;

DOI:10.1134/S1070428008120208

Reference yield: 85.0%

2,3,5-trimethyl-pyridine (695-98-7) + methyl iodide (74-88-4) → 2,3,5,6-tetramethylpyridine (3748-84-3) + 2-ethyl-3,5-dimethylpyridine (1123-96-2)

Guidance literature:

2,3,5-trimethyl-pyridine; With n-butyllithium; In diethyl ether; hexane; for 1.16667h; Inert atmosphere;

methyl iodide; In diethyl ether; hexane; at -78 - 20 ℃; Inert atmosphere;

DOI:10.1039/c1gc15408g

upstream raw materials:

2S-amino-1-propanol

2-methyl-2-pentenal

acetamide

propionaldehyde

Downstream raw materials:

2,3,5-pyridinetricarboxylic acid

3,5-dimethylpicolinic acid

Refernces

• 1、 Vijn,Arts,Green,Castelijns. "Synthesis of alkyl- and aryl-substituted pyridines from (α,β-unsaturated) imines or oximes and carbonyl compounds". . p. 573 - 578. Retrieved 1994.
• 2、 Mohan. "-". . p. 3982. Retrieved 1970.
• 3、 -. "ZEOLITE CATALYST". Paragraph 0124. . Retrieved 2019/05/22.
• 4、 Khusnutdinova, Julia R.,Ben-David, Yehoshoa,Milstein, David. "Direct deamination of primary amines by water to produce alcohols". supporting information. p. 6269 - 6272. Retrieved 2013/07/19.