Technology Process of Heptanoic acid, 3-hydroxy-5-(methoxymethoxy)-7-(phenylmethoxy)-,
1,1-dimethylethyl ester, (3S,5S)-
There total 4 articles about Heptanoic acid, 3-hydroxy-5-(methoxymethoxy)-7-(phenylmethoxy)-,
1,1-dimethylethyl ester, (3S,5S)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen;
Ikariya-Mashima's catalyst;
In
methanol;
at 20 ℃;
for 8h;
under 60004.8 Torr;
DOI:10.1055/s-2005-862351
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 82 percent / H2 / {Ru[(S)-SYNPHOS]Br2} / ethanol / 14 h / 80 °C / 8250.66 Torr
2.1: 86 percent / P2O5 / CHCl3 / 0.25 h / 0 °C
3.1: LDA / tetrahydrofuran / -40 °C
3.2: 84 percent / tetrahydrofuran / 4.5 h / -40 °C
4.1: 93 percent / H2 / Ikariya-Mashima's catalyst / methanol / 8 h / 20 °C / 60004.8 Torr
With
hydrogen; phosphorus pentoxide; lithium diisopropyl amide;
RuBr2[(S)-(C6H2OCH2CH2OP(C6H5)2)2]; Ikariya-Mashima's catalyst;
In
tetrahydrofuran; methanol; ethanol; chloroform;
DOI:10.1055/s-2005-862351
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 86 percent / P2O5 / CHCl3 / 0.25 h / 0 °C
2.1: LDA / tetrahydrofuran / -40 °C
2.2: 84 percent / tetrahydrofuran / 4.5 h / -40 °C
3.1: 93 percent / H2 / Ikariya-Mashima's catalyst / methanol / 8 h / 20 °C / 60004.8 Torr
With
hydrogen; phosphorus pentoxide; lithium diisopropyl amide;
Ikariya-Mashima's catalyst;
In
tetrahydrofuran; methanol; chloroform;
DOI:10.1055/s-2005-862351
