2-Nitrophenylhydrazine Hydrochloride

Base Information

• Chemical Name: 2-Nitrophenylhydrazine Hydrochloride
• CAS No.: 6293-87-4
• Molecular Formula: C6H7 N3 O2 . Cl H
• Molecular Weight: 189.601
• Hs Code.: 29280000
• European Community (EC) Number: 678-267-3
• NSC Number: 9184
• DSSTox Substance ID: DTXSID60971848
• Mol file: 6293-87-4.mol

Synonyms:2-nitrophenylhydrazine;2-nitrophenylhydrazine hydrochloride;2-nitrophenylhydrazine monohydrochloride;2-NPH;o-nitrophenylhydrazine

Chemical Property of 2-Nitrophenylhydrazine Hydrochloride

Chemical Property:

• Vapor Pressure: 0.000469mmHg at 25°C
• Boiling Point: 314.3 °C at 760 mmHg
• Flash Point: 143.9 °C
• PSA: 83.87000
• LogP: 2.97890
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 189.0305042
• Heavy Atom Count: 12
• Complexity: 145

Purity/Quality:

99% ^*data from raw suppliers

(2-Nitrophenyl)hydrazineHydrochloride(1:1) ^*data from reagent suppliers

Safty Information:

• Statements: 20-21-36-37-22
• Safety Statements: 26-36/37/39-44-28

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)NN)[N+](=O)[O-].Cl

Technology Process of 2-Nitrophenylhydrazine Hydrochloride

There total 1 articles about 2-Nitrophenylhydrazine Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-nitro-aniline (88-74-4) → o-nitrophenylhydrazine hydrochloride (6293-87-4)

Guidance literature:

2-nitro-aniline; With hydrogenchloride; sodium nitrite; In water; at -10 - 0 ℃; for 0.5h;

With hydrogenchloride; tin(II) chloride dihdyrate; In water;

DOI:10.1021/jf4046683

Reference yield: 92.0%

C15H14F3NO3 (1332635-72-9) + o-nitrophenylhydrazine hydrochloride (6293-87-4) → 3-(2-nitrophenylhydrazonotrifluoroethyl)-7-(N,N-diethylamino)coumarin

Guidance literature:

With toluene-4-sulfonic acid; In chlorobenzene; Reflux;

DOI:10.1016/j.dyepig.2011.05.011

Reference yield: 82.0%

2-oxo-propionic acid ethyl ester (617-35-6) + o-nitrophenylhydrazine hydrochloride (6293-87-4) → 2-(2-(2-nitrophenyl)hydrazono)propionic acid ethyl ester (292853-66-8)

Guidance literature:

In ethanol; at 20 ℃; for 0.166667h;

DOI:10.1016/j.bmc.2014.01.047

upstream raw materials:

2-nitro-aniline

Downstream raw materials:

1-(2-nitrophenyl)pyrazol

4-nitro-1-(2-nitro-phenyl)-1H-pyrazole

3,5-dimethyl-1-(2-nitrophenyl)-1H-pyrazole

2,6-di-tert-butyl-1-oxo-1λ⁴-[1,2,6]thiadiazinane-3,4,5-trione 4-[(2-nitro-phenyl)-hydrazone]

Refernces