Flumetsulam

Base Information

• Chemical Name: Flumetsulam
• CAS No.: 98967-40-9
• Molecular Formula: C12H9F2N5O2S
• Molecular Weight: 325.299
• Hs Code.: 2933599590
• European Community (EC) Number: 619-383-6
• UNII: X89F0S6LW8
• DSSTox Substance ID: DTXSID4032615
• Nikkaji Number: J653.649B
• Wikidata: Q26840836
• ChEMBL ID: CHEMBL1389671
• Mol file: 98967-40-9.mol

Synonyms:flumetsulam;N-(2,6-difluorophenyl)-5-methyl(1,2,4)-triazol(1,5-a)pyrimidine-2-sulfonamide

Chemical Property of Flumetsulam

Chemical Property:

• Vapor Pressure: 0Pa at 25℃
• Melting Point: 251-253oC
• Refractive Index: 1.703
• PKA: 4.6(at 25℃)
• Flash Point: 93℃
• PSA: 97.63000
• Density: 1.66 g/cm³
• LogP: 2.66550
• Storage Temp.: 0-6°C
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 3
• Exact Mass: 325.04450204
• Heavy Atom Count: 22
• Complexity: 492

Purity/Quality:

99% ^*data from raw suppliers

Flumetsulam ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi,N,Xn
• Statements: 20-50-57
• Safety Statements: 61

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=NC2=NC(=NN2C=C1)S(=O)(=O)NC3=C(C=CC=C3F)F
• Uses: Herbicide. Flumetsulam is a ighly active herbicide of the triazolopyrimidine sulfonanilide class. Flumetsulam act by inhibiting acetolactate synthase. Flumetsulam exhibits broad spectrum activity on broadleaf weed species with selectivity to several major agronomic crops in soil and foliar applications.

Technology Process of Flumetsulam

There total 4 articles about Flumetsulam which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

N-(3-(((2,6-difluorophenyl)amino)sulfonyl)-1H-1,2,4-triazol-5-yl)amine (113171-12-3) + acetylacetaldehyde dimethyl acetal (5436-21-5) → N-(2,6-difluorophenyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide (98967-40-9)

Guidance literature:

With hydrogenchloride; sodium hydroxide; sodium carbonate; sodium chloride; In water;

Reference yield:

5-methyl-1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonyl chloride (98165-60-7) + 2,6-difluoroaniline (5509-65-9) → N-(2,6-difluorophenyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide (98967-40-9)

Guidance literature:

With hydrogenchloride; dimethylsulfide; chlorine; sulfinyl imine; In quinoline; dichloromethane; water;

Reference yield:

5-methyl-1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonyl chloride (98165-60-7) + IN aqueous hydrochloric acid + 2,6-difluoroaniline (5509-65-9) → N-(2,6-difluorophenyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide (98967-40-9)

Guidance literature:

With dimethylsulfide; chlorine; sulfinyl imine; In quinoline; dichloromethane; water;

upstream raw materials:

5-methyl-1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonyl chloride

2,6-difluoroaniline

N-(3-(((2,6-difluorophenyl)amino)sulfonyl)-1H-1,2,4-triazol-5-yl)amine

acetylacetaldehyde dimethyl acetal

Refernces

• 1、 -. "N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds". . . Retrieved 2008/06/13.
• 2、 -. "Aqueous process for the preparation of 5-methyl-n-(aryl)-1,2,4-triazolo(1,5-A)pyrimidine-2-sulfonamides". . . Retrieved 2008/06/13.