Thiodrol

Base Information

• Chemical Name: Thiodrol
• CAS No.: 2363-58-8
• Molecular Formula: C19H30OS
• Molecular Weight: 306.51
• NSC Number: 194684
• DSSTox Substance ID: DTXSID30859720
• Wikidata: Q5383718
• Mol file: 2363-58-8.mol

Synonyms:10275-S;2 alpha,3 alpha-epithio-5 alpha-androstan-17 beta-ol;epithiostanol;epitiostanol;Thiodrol

Chemical Property of Thiodrol

Chemical Property:

• Vapor Pressure: 5.56E-09mmHg at 25°C
• Melting Point: 127-128°
• Refractive Index: 1.579
• Boiling Point: 424.407 °C at 760 mmHg
• PKA: 15.10±0.60(Predicted)
• Flash Point: 206.05 °C
• PSA: 45.53000
• Density: 1.138 g/cm³
• LogP: 4.48390
• Water Solubility.: 1.2mg/L(37 oC)
• XLogP3: 5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 306.20173675
• Heavy Atom Count: 21
• Complexity: 465

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC12CCC3C(C1CCC2O)CCC4C3(CC5C(C4)S5)C
• Uses: An anabolic steroid that exhibits androgenic, myogenic, anabolic, anticatabolic, progestational, deciduomatogenic, and antiestrogenic activities. An anti-estrogen with anti-mammry cancer agent.
• Therapeutic Function: Antineoplastic

Technology Process of Thiodrol

There total 1 articles about Thiodrol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 17β-Hydroxy-5α-androstan-2α,3α-episulfid (2136-25-6,2363-58-8)

Guidance literature:

2β-Mesyloxy-3α-thiocyanoto-17β-acetoxy-5α-androstan, KOH in Diglyme; als C19H30O5*1/4H2O; neben 17β-Acetoxy-2α,3α-epithio-5α-androstan;

DOI:10.1016/S0040-4020(01)98273-0