Mesitil

Base Information

• Chemical Name: Mesitil
• CAS No.: 4746-81-0
• Molecular Formula: C20H22O2
• Molecular Weight: 294.393
• Mol file: 4746-81-0.mol

Synonyms:1,2-dimesityldiketone;2,4,6,2',4',6'-hexamethylbenzil;

Chemical Property of Mesitil

Chemical Property:

• PSA: 34.14000
• LogP: 4.60260

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Mesitil

There total 41 articles about Mesitil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

mesitylene-2-carboxylic acid chloride (938-18-1) → mesitil (4746-81-0) + <1,2-Bis(2,4,6-trimethylphenyl)-1,2-ethendiyl>-bis(2,4,6-trimethylbenzoat) (86156-73-2)

Guidance literature:

With lithium amalgam; In diethyl ether; at 25 ℃;

Reference yield: 67.0%

carbon monoxide (201230-82-2) + mesityllithium (5806-59-7) → mesitil (4746-81-0) + 1,3,5-trimethyl-benzene (108-67-8)

Guidance literature:

In tetrahydrofuran; at -50 ℃; under 759.811 Torr;

DOI:10.1039/a809045i

Reference yield: 38.0%

2,2-dimesitoylhexamethyltrisilane + methyl iodide (74-88-4) → mesitil (4746-81-0)

Guidance literature:

2,2-dimesitoylhexamethyltrisilane; With tris(trimethylsilyl)silyllithium; In tetrahydrofuran; diethyl ether; at -80 ℃; for 1h; Inert atmosphere;

methyl iodide; In tetrahydrofuran; diethyl ether; at -80 ℃; Inert atmosphere;

DOI:10.1021/om100643d

upstream raw materials:

2,3-dihydroxy-1,4-dimesityl-butane-1,4-dione

2,3-dihydroxy-1,4-dimesityl-but-2-ene-1,4-dione

copper diacetate

acetic acid

Downstream raw materials:

mesytaldehyde

mesitylenecarboxylic acid

3,3'-dibromo-2,4,6,2',4',6'-hexamethyl-benzoin

2,4,6-trimethylbenzaldehyde-1-d

Refernces

• 1、 -. "Functional material based on stable chemical structure". . . Retrieved 2021/08/25.
• 2、 Nudelman, Norma,Schulz, Hernan. "Synthesis of highly hindered 1,2-diaryl diketones and of cis- and trans-1,2-diacetoxy-1,2-bis(aryl)ethenes". . p. 422 - 423. Retrieved 2007/10/03.