Diethyl 3,3'-IMinodipropionate

Base Information

• Chemical Name: Diethyl 3,3'-IMinodipropionate
• CAS No.: 3518-88-5
• Molecular Formula: C10H19NO4
• Molecular Weight: 217.265
• Mol file: 3518-88-5.mol

Synonyms:Diethyl 3,3'-Iminodipropionate;2,2'-dicarboethoxydiethylamine;diethyl 3,3'-azanediyldipropanoate;N,N-bis-(1-ethoxy-carbonyleth-2-yl)amine;bis<2-(ethoxycarbonyl)ethyl>amin;diethyl 3,3'-iminodipropanoate;3,3'-iminobis(ethyl propionate);3,3'-Iminodipropionic Acid Diethyl Ester;

Chemical Property of Diethyl 3,3'-IMinodipropionate

Chemical Property:

• Refractive Index: 1.4390-1.4430
• Boiling Point: 292.4°Cat760mmHg
• Flash Point: 130.6°C
• PSA: 64.63000
• Density: 1.037g/cm³
• LogP: 0.87330
• Storage Temp.: 0-10°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

Diethyl 3,3'-Iminodipropionate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Diethyl 3,3'-IMinodipropionate

There total 17 articles about Diethyl 3,3'-IMinodipropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

N,N-bis(2-ethoxycarbonylethyl)benzylamine (6938-07-4) → 3,3'-imino-di-propionic acid diethyl ester (3518-88-5)

Guidance literature:

With palladium 10% on activated carbon; ammonium formate; In ethanol; for 2h; Reflux;

DOI:10.1016/j.bmc.2011.06.076

Reference yield: 67.0%

ethyl acrylate (140-88-5,9003-32-1) → 3,3'-imino-di-propionic acid diethyl ester (3518-88-5)

Guidance literature:

ethyl acrylate; With ammonium hydroxide; hydroxylamine hydrochloride; In ethanol; at 20 ℃; for 15h;

With indium; ammonium chloride; In ethanol; for 7.5h; Heating;

DOI:10.1021/ol034434l

Reference yield: 49.0%

ethyl acrylate (140-88-5,9003-32-1) → Tris<2-(ethoxycarbonyl)ethyl>amin (3330-10-7) + 3,3'-imino-di-propionic acid diethyl ester (3518-88-5)

Guidance literature:

With ammonia; for 24h;

upstream raw materials:

3-amino-propionic acid ethyl ester

ethanol

ethyl 3-iodopropanoate

sodium ethanolate

Downstream raw materials:

N-(p-Jodobenzyl)-3,3'-iminodipropionsaeurediaethylester

3,3'-iminodipropanoic acid tosylamide

3-[(2-amino-ethyl)-(3-hydroxy-propyl)-amino]-propan-1-ol

guvacine

Refernces

• 1、 -. "Synthesis method of bacterial infection resistant medicine intermediate". Paragraph 0026; 0034; 0035. . Retrieved 2018/07/30.
• 2、 -. "RECYCLABLE CATALYSTS FOR CHLORINATION OF ORGANIC ACIDS AND ALCOHOLS". Paragraph 0066-0068. . Retrieved 2017/10/10.