3-methoxyhexanoic acid

Base Information

• Chemical Name: 3-methoxyhexanoic acid
• CAS No.: 5413-09-2
• Molecular Formula: C₇H₁₄O₃
• Molecular Weight: 146.186
• Mol file: 5413-09-2.mol

Synonyms:NSC 231380

Chemical Property of 3-methoxyhexanoic acid

Chemical Property:

• Vapor Pressure: 0.0302mmHg at 25°C
• Boiling Point: 226.2°Cat760mmHg
• Flash Point: 85.8°C
• Density: 1.005g/cm³

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-methoxyhexanoic acid

There total 3 articles about 3-methoxyhexanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-methoxy-caproic acid methyl ester (54905-29-2) → rac-methyl 3-methoxyhexanoic acid (5413-09-2)

Guidance literature:

With sodium hydroxide; In methanol;

DOI:10.1021/np030215x

Reference yield:

methyl 3-hydroxyhexanoate (21188-58-9) → rac-methyl 3-methoxyhexanoic acid (5413-09-2)

Guidance literature:

Multi-step reaction with 2 steps

1: KOH; Et₃N / petroleum ether / 5 h / 20 °C

2: aq. NaOH / methanol

With potassium hydroxide; sodium hydroxide; triethylamine; In methanol; Petroleum ether;

DOI:10.1021/np030215x

Reference yield:

→ rac-methyl 3-methoxyhexanoic acid (5413-09-2)

Guidance literature:

With formic acid; oxygen; cobalt(II) acetate;

upstream raw materials:

3-methoxy-caproic acid methyl ester

methyl 3-hydroxyhexanoate

Refernces