Technology Process of Butanoic acid, 2-methyl-4-(phenylmethoxy)-, (R)-
There total 16 articles about Butanoic acid, 2-methyl-4-(phenylmethoxy)-, (R)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(S)-4-(benzyloxy)-N-((1R,2R)-1-hydroxy-1-phenylpropan-2-yl)-N,2-dimethylbutanamide;
With
methanesulfonic acid;
In
tetrahydrofuran;
at 70 ℃;
for 1h;
Inert atmosphere;
With
lithium borohydride;
In
tetrahydrofuran;
at 0 - 20 ℃;
Inert atmosphere;
With
sodium hydroxide;
In
tetrahydrofuran; water;
at 20 ℃;
for 18h;
Inert atmosphere;
DOI:10.1002/ejoc.202001216
- Guidance literature:
-
(2'R,4R)-3-(4'-benzyloxy-2'-methylbutanoyl)-4,5,5-triphenyloxazolidinone;
With
dihydrogen peroxide; lithium hydroxide;
In
tetrahydrofuran; water;
at 0 - 25 ℃;
for 1.3h;
With
hydrogenchloride;
In
tetrahydrofuran; water;
DOI:10.1016/j.tetlet.2012.06.133
- Guidance literature:
-
Multi-step reaction with 2 steps
1: palladium on activated charcoal; hydrogen / ethanol / 16 h / 25 °C
2: dihydrogen peroxide; lithium hydroxide / tetrahydrofuran; water / 1.3 h / 0 - 25 °C
With
palladium on activated charcoal; hydrogen; dihydrogen peroxide; lithium hydroxide;
In
tetrahydrofuran; ethanol; water;
DOI:10.1016/j.tetlet.2012.06.133