Trelagliptin

Base Information

• Chemical Name: Trelagliptin
• CAS No.: 865759-25-7
• Molecular Formula: C18H20FN5O2
• Molecular Weight: 357.38200
• Mol file: 865759-25-7.mol

Synonyms:SYR-472;Benzonitrile, 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-4-fluoro-;Trelagliptin (USAN);SYR 472;2-[[6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxopyrimidin-1-yl]methyl]-4-fluorobenzonitrile;UNII-Q836OWG55H;(R)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile;

Chemical Property of Trelagliptin

Chemical Property:

• Appearance/Colour: White to off-white solid
• Boiling Point: 519.0±60.0 °C(Predicted)
• PKA: 9.88±0.20(Predicted)
• PSA: 97.05000
• Density: 1.38±0.1 g/cm3(Predicted)
• LogP: 1.29888
• Solubility.: ≥11.6 mg/mL in DMSO; ≥3.68 mg/mL in EtOH with gentle warming and ultrasonic; ≥93.8 mg/mL in H2O

Purity/Quality:

99% ^*data from raw suppliers

(S)-2-((6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Trelagliptin is a highly selective, long-acting dipeptidyl peptidase IV (DPP-4) inhibitor. This inhibitor provides sustained reduction of plasma DPP-4 activity and lowering of blood glucose in animal models of diabetes.