Tyrphostin A46

Base Information

• Chemical Name: Tyrphostin A46
• CAS No.: 118409-59-9
• Molecular Formula: C10H8N2O3
• Molecular Weight: 204.1821
• European Community (EC) Number: 634-191-2,878-366-3
• NSC Number: 666250,638077
• UNII: ARL2OF9022
• Nikkaji Number: J377.764B,J412.912A
• Wikidata: Q76304046
• NCI Thesaurus Code: C1540
• ChEMBL ID: CHEMBL296407
• Mol file: 118409-59-9.mol

Synonyms:3,4-dihydroxy-alpha-cyanocinnamamide;3,4-dihydroxybenzylidene cyanoacetamide;AG 99;alpha-cyano-(3,4-dihydroxy)cinnamide;tyrphostin 46;tyrphostin A46;tyrphostin AG99;tyrphostin B40

Chemical Property of Tyrphostin A46

Chemical Property:

• Appearance/Colour: Off-white solid
• Vapor Pressure: 1.83E-12mmHg at 25°C
• Refractive Index: 1.71
• Boiling Point: 544.4 °C at 760 mmHg
• Flash Point: 283 °C
• PSA: 107.34000
• Density: 1.482 g/cm³
• LogP: 1.19038
• Storage Temp.: 2-8°C
• XLogP3: 0.4
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 204.05349212
• Heavy Atom Count: 15
• Complexity: 329

Purity/Quality:

98%min ^*data from raw suppliers

AG 99 ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1C=C(C#N)C(=O)N)O)O
• Isomeric SMILES: C1=CC(=C(C=C1/C=C(\C#N)/C(=O)N)O)O
• Uses: Tyrphostin AG 99 is a potent, cell-permeable and reversible inhibitor of EGFR and EGF-dependent cell proliferation.