3,4-Diaminofurazan

Base Information

• Chemical Name: 3,4-Diaminofurazan
• CAS No.: 17220-38-1
• Molecular Formula: C2H4N4O
• Molecular Weight: 100.08
• Hs Code.: 29349990
• Mol file: 17220-38-1.mol

Synonyms:Furazan,diamino- (8CI);3,4-Diamino-1,2,5-oxadiazole;3,4-Furazandiamine;

Chemical Property of 3,4-Diaminofurazan

Chemical Property:

• Appearance/Colour: white to slightly beige crystalline powder
• Vapor Pressure: 0.056mmHg at 25°C
• Melting Point: 178-183 °C
• Refractive Index: 1.621
• Boiling Point: 304 °C at 760 mmHg
• PKA: 1.31±0.47(Predicted)
• Flash Point: 137.7 °C
• PSA: 90.96000
• Density: 1.582 g/cm³
• LogP: 0.39640
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

3,4-Diaminofurazan ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi,Xn
• Statements: 36/37/38-22
• Safety Statements: 24/25-26-36/37

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 3,4-Diaminofurazan is a building block used to prepare magnesium and zinc alkynylated salicylaldehyde-diamine Schiff base complexes. 3,4-Diaminofurazan is also used to prepare aryl(hydroxy)oxadiazolopyrazines via oxidation of acetophenones followed by heterocyclization with antibacterial-activities.

Technology Process of 3,4-Diaminofurazan

There total 14 articles about 3,4-Diaminofurazan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

1H-indene-1,3(2H)-dione (606-23-5) + 4-azido-1,2,5-oxadiazol-3-amine (78350-49-9) → diazobindone + 2-diazo-indan-1,3-dione (1807-49-4) + 3,4-diaminofurazan (17220-38-1)

Guidance literature:

With magnesium carbonate; In ethanol; for 0.0833333h;

DOI:10.1070/mc2002v012n04abeh001589

Reference yield: 70.0%

diaminoglyoxime (2580-79-2) → 3,4-diaminofurazan (17220-38-1)

Guidance literature:

With potassium hydroxide; at 170 - 180 ℃; for 2h;

Reference yield: 70.0%

glyoxime (557-30-2) → 3,4-diaminofurazan (17220-38-1)

Guidance literature:

With sodium hydroxide; hydroxylamine hydrochloride; microwave irradiation;

upstream raw materials:

diaminoglyoxime

5-trifluoromethyl-1,2,4-oxadiazole-3-carboxyamidoxime

3,3’-bi-(5-trifluoromethyl-1,2,4-oxadiazole)

1H-indene-1,3(2H)-dione

Downstream raw materials:

5-(4-chloro-phenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine

4-phenylazo-furazan-3-ylamine

5-(4-methoxyphenyl)furazano[3,4-b]pyrazine

5,6-diphenyl-[1,2,5]oxadiazolo[3,4-b]pyrazine

Refernces

• 1、 Zhang, Jiaheng,Shreeve, Jean'Ne M.. "3,3′-Dinitroamino-4,4′-azoxyfurazan and its derivatives: An assembly of diverse N-O building blocks for high-performance energetic materials". . p. 4437 - 4445. Retrieved 2014.
• 2、 Sun, Qi,Li, Xin,Lin, Qiuhan,Lu, Ming. "Tetracyclic pyrazine-fused furazans as insensitive energetic materials: Syntheses, structures, and properties". . p. 8034 - 8037. Retrieved 2018.
• 3、 Zelenin, Alexander K.,Trudell, Mark L.. "A Two-Step Synthesis of Diaminofurazan and Synthesis of N-Monoarylmethyl and N,N'-Diarylmethyl Derivatives". . p. 1057 - 1060. Retrieved 1997.
• 4、 -. "Tetrazine-furazan ring high-nitrogen energetic compound and synthesis method thereof". Paragraph 0015; 0027-0029. . Retrieved 2020/11/25.