desaminosulfamethazine

Base Information

• Chemical Name: desaminosulfamethazine
• CAS No.: 6149-31-1
• Molecular Formula: C12H13 N3 O2 S
• Molecular Weight: 263.32
• Mol file: 6149-31-1.mol

Synonyms:Deaminosulfamethazine;Desaminosulfadimidine; Desaminosulfamethazine

Chemical Property of desaminosulfamethazine

Chemical Property:

• Vapor Pressure: 8.35E-09mmHg at 25°C
• Melting Point: 150-152 °C
• Boiling Point: 464.4°C at 760 mmHg
• PKA: 7.07±0.10(Predicted)
• Flash Point: 234.7°C
• PSA: 80.33000
• Density: 1.332g/cm³
• LogP: 3.04800

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of desaminosulfamethazine

There total 2 articles about desaminosulfamethazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

sulfadimesine (57-68-1) → N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide (6149-31-1)

Guidance literature:

With boron trifluoride diethyl etherate; sodium nitrite; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

DOI:10.1002/chem.201803347

Reference yield:

2-Amino-4,6-dimethylpyrimidine (767-15-7,184433-59-8) + benzenesulfonyl chloride (98-09-9) → N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide (6149-31-1)

Guidance literature:

DOI:10.1021/jo01180a011

upstream raw materials:

2-Amino-4,6-dimethylpyrimidine

benzenesulfonyl chloride

sulfadimesine

Refernces