(S)-Phenprocoumon

Base Information

• Chemical Name: (S)-Phenprocoumon
• CAS No.: 3770-63-6
• Molecular Formula: C18H16O3
• Molecular Weight: 280.323
• Hs Code.: 2932209090
• Mol file: 3770-63-6.mol

Synonyms:

Chemical Property of (S)-Phenprocoumon

Chemical Property:

• Vapor Pressure: 8.68E-08mmHg at 25°C
• Boiling Point: 419.5°Cat760mmHg
• Flash Point: 151.8°C
• PSA: 50.44000
• Density: 1.261g/cm³
• LogP: 4.04050

Purity/Quality:

>95% ^*data from raw suppliers

(S)-Phenprocoumon ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (S)-Phenprocoumon acts primarily as an oral anti-coagulant.

Technology Process of (S)-Phenprocoumon

There total 2 articles about (S)-Phenprocoumon which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phenprocoumon (435-97-2,5999-27-9) → [13C]-(-)-Phenprocoumon (3770-63-6,5999-27-9)

Guidance literature:

With quinindine; Resolution of racemate;

DOI:10.1007/s10870-019-00813-5

Reference yield:

→ [13C]-(-)-Phenprocoumon (3770-63-6,5999-27-9)

Guidance literature:

aus d. rac.-Verb. ueber d. Chinidin-Salz (Kryst. aus Ethanol + CHCl3; <α>(d)²³: +75grad (Butanon-(2), c = 1));

Reference yield:

[13C]-(-)-Phenprocoumon (3770-63-6,5999-27-9) → (-)(R)-3-Phenyl-1,1-bis-(2-methoxy-phenyl)-pentanol-(1) (2732-19-6)

Guidance literature:

Multi-step reaction with 3 steps

1: aq. Na₂CO₃

2: aq. NaOH

3: (i) Mg, (ii) /BRN= 7269410/

With sodium hydroxide; sodium carbonate;

upstream raw materials:

phenprocoumon

Downstream raw materials:

(-)(R)-2-(3-Phenyl-pentanoyl)phenol

1-(2-methoxyphenyl)-3-phenylpentan-1-one

(-)(R)-3-Phenyl-1,1-bis-(2-methoxy-phenyl)-pentanol-(1)

Refernces