4-bromo-2-fluoro-N-isopropylbenzamide

Base Information

• Chemical Name: 4-bromo-2-fluoro-N-isopropylbenzamide
• CAS No.: 877383-76-1
• Molecular Formula: C₁₀H₁₁BrFNO
• Molecular Weight: 260.106
• Hs Code.: 2924299090
• Mol file: 877383-76-1.mol

Synonyms:4-Bromo-2-fluoro-N-isopropylbenzamide;

Chemical Property of 4-bromo-2-fluoro-N-isopropylbenzamide

Chemical Property:

• PSA: 32.59000
• LogP: 3.30120

Purity/Quality:

99% ^*data from raw suppliers

4-Bromo-2-fluoro-N-isopropylbenzamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-bromo-2-fluoro-N-isopropylbenzamide

There total 2 articles about 4-bromo-2-fluoro-N-isopropylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

isopropylamine (75-31-0) + 2-fluoro-4-bromobenzoic acid (112704-79-7) → 4-bromo-2-fluoro-N-(1-methylethyl)-benzamide (877383-76-1)

Guidance literature:

2-fluoro-4-bromobenzoic acid; With N-ethyl-N,N-diisopropylamine; HATU; In dichloromethane; for 0.166667h;

isopropylamine; for 1.5h;

Reference yield:

→ 4-bromo-2-fluoro-N-(1-methylethyl)-benzamide (877383-76-1)

Guidance literature:

upstream raw materials:

isopropylamine

2-fluoro-4-bromobenzoic acid

Refernces

• 1、 -. "BIPHENYLOXYACETIC ACID DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASE". Page/Page column 61. . Retrieved 2008/06/13.