TRIS(4-TRIFLUOROMETHYLPHENYL)PHOSPHINE

Base Information

• Chemical Name: TRIS(4-TRIFLUOROMETHYLPHENYL)PHOSPHINE
• CAS No.: 13406-29-6
• Molecular Formula: C21H12F9P
• Molecular Weight: 466.286
• Hs Code.: 29319090
• Mol file: 13406-29-6.mol

Synonyms:Phosphine,tris(a,a,a-trifluoro-p-tolyl)- (7CI,8CI);Tris[4-(trifluoromethyl)phenyl]phosphine;Tris[p-(trifluoromethyl)phenyl]phosphine;

Chemical Property of TRIS(4-TRIFLUOROMETHYLPHENYL)PHOSPHINE

Chemical Property:

• Appearance/Colour: white to light yellow crystal powder
• Vapor Pressure: 1.01E-05mmHg at 25°C
• Melting Point: 70-75 °C
• Boiling Point: 382.8 °C at 760 mmHg
• Flash Point: 185.3 °C
• PSA: 13.59000
• LogP: 6.50120
• Storage Temp.: Inert atmosphere,Room Temperature
• Water Solubility.: Insoluble in water.

Purity/Quality:

98%,99%, ^*data from raw suppliers

Tris(4-(trifluoromethyl)phenyl)phosphine 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: Tris[4-(trifluoromethyl)phenyl]phosphine is a raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals.

Technology Process of TRIS(4-TRIFLUOROMETHYLPHENYL)PHOSPHINE

There total 10 articles about TRIS(4-TRIFLUOROMETHYLPHENYL)PHOSPHINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

tris(4-trifluoromethylphenyl)phosphine oxide (13406-27-4) → tris(para-trifluoromethyl)phenyl phosphine (13406-29-6)

Guidance literature:

With diisobutylaluminium hydride; In cyclohexane; at 72 ℃; for 14h;

DOI:10.1021/jo7024064

Reference yield: 72.0%

p-trifluoromethylphenyl bromide (402-43-7) → tris(para-trifluoromethyl)phenyl phosphine (13406-29-6)

Guidance literature:

p-trifluoromethylphenyl bromide; With magnesium dihydride; In diethyl ether; at 20 ℃; for 1h;

With phosphorus trichloride; In diethyl ether; at 20 ℃; for 1h;

DOI:10.1002/adsc.201500712

Reference yield: 53.0%

(4-(trifluoromethyl)phenyl)zinc(II) bromide (198345-82-3) → tris(para-trifluoromethyl)phenyl phosphine (13406-29-6)

Guidance literature:

With phosphorus trichloride; In acetonitrile; at 20 ℃; for 2h;

DOI:10.1055/s-2006-939056

upstream raw materials:

p-trifluoromethylphenyl bromide

4-(trifluoromethyl)phenylmagnesium bromide

(4-(trifluoromethyl)phenyl)zinc(II) bromide

tris(4-trifluoromethylphenyl)phosphine oxide

Downstream raw materials:

N-phenyl-P,P,P-trisphospha-λ⁵-azene

methyltris<4-(trifluoromethyl)phenyl>phosphonium tosylate

(η(5)-C5H5)RuCl(P(p-CF3C6H4)3)2

cis-dichlorobis{tris(4-(trifluoromethyl)phenyl)phosphane}platinum(II)

Refernces

• 1、 Gschwind, Ruth M.,Mende, Michael,Scott, Daniel J.,Streitferdt, Verena,Till, Marion,Wolf, Robert. "Photochemical transformation of chlorobenzenes and white phosphorus into arylphosphines and phosphonium salts". supporting information. p. 1100 - 1103. Retrieved 2022/02/03.
• 2、 Landais, Yannick,Laye, Claire,Lusseau, Jonathan,Robert, Frédéric. "The Trityl-Cation Mediated Phosphine Oxides Reduction". supporting information. p. 3035 - 3043. Retrieved 2021/05/10.