2,5-difluoro-4-methylaniline

Base Information

• Chemical Name: 2,5-difluoro-4-methylaniline
• CAS No.: 878285-14-4
• Molecular Formula: C₇H₇F₂N
• Molecular Weight: 143.136
• Hs Code.: 2921490090
• Mol file: 878285-14-4.mol

Synonyms:2,5-difluoro-4-aminotoluene;QC-7448;

Chemical Property of 2,5-difluoro-4-methylaniline

Chemical Property:

• PSA: 26.02000
• LogP: 2.43660
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

99% ^*data from raw suppliers

2,5-Difluoro-4-methylaniline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,5-difluoro-4-methylaniline

There total 2 articles about 2,5-difluoro-4-methylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.8%

→ 2,5-difluoro-4-methylaniline (878285-14-4)

Guidance literature:

With hydrogen; In methanol; at 55 - 60 ℃; for 3h; under 60006 Torr; Sealed tube;

Reference yield:

p-toluidine (106-49-0,12221-03-3) → 3,5-difluoro-4-methylaniline (878285-13-3) + 2,5-difluoro-4-methylaniline (878285-14-4) + 2-fluoro-4-methylaniline (452-80-2) + 3-fluoro-4-methyl-phenylamine (452-77-7)

Guidance literature:

With trifluorormethanesulfonic acid; fluorine; at 20 ℃; Title compound not separated from byproducts;

DOI:10.1016/j.jfluchem.2005.02.013

upstream raw materials:

p-toluidine

Refernces

• 1、 -. "2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES". Page/Page column 7. . Retrieved 2009/03/07.