Tri-o-tolylthiophosphate

Base Information

• Chemical Name: Tri-o-tolylthiophosphate
• CAS No.: 631-45-8
• Molecular Formula: C21H21O3PS
• Molecular Weight: 384.436
• Mol file: 631-45-8.mol

Synonyms:Tri-o-tolyl phosphorothioate;O.O.O-Tri-o-tolyl-thiophosphat;O,O,O-Tris(2-methylphenyl) thiophosphate;Tri-o-cresyl phosphorothionate;Tri-o-cresyl phosphorothioate;Tri-o-cresyl thiophosphate;Thiophosphorsaeure-O,O',O''-tri-o-tolylester;O,O,O-tri-o-tolyl phosphorothioate;thiophosphoric acid O,O',O''-tri-o-tolyl ester;o-Tolyl phosphorothioate;tri-o-tolylthiophosphate;

Chemical Property of Tri-o-tolylthiophosphate

Chemical Property:

• Vapor Pressure: 8.55E-09mmHg at 25°C
• Boiling Point: 476.8°C at 760 mmHg
• Flash Point: 242.1°C
• PSA: 69.59000
• Density: 1.222g/cm³
• LogP: 7.02370

Purity/Quality:

98%min ^*data from raw suppliers

TRI-ORTHO-CRESYL THIOPHOSPHATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Tri-o-tolylthiophosphate

There total 7 articles about Tri-o-tolylthiophosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

ortho-cresol (95-48-7,77504-84-8) → O,O,O-tri-o-tolyl phosphorothioate (631-45-8)

Guidance literature:

ortho-cresol; With potassium phosphate; diphenyl diselenide; phosphorus; In dimethyl sulfoxide; toluene; at 60 ℃; for 4h; Inert atmosphere;

With sulfur; In dimethyl sulfoxide; toluene; at 60 ℃; for 4h; Inert atmosphere;

Reference yield: 79.4%

ortho-cresol (95-48-7,77504-84-8) → O,O-di-o-tolyl hydrogen phosphorodithioate (34381-74-3) + O,O,O-tri-o-tolyl phosphorothioate (631-45-8)

Guidance literature:

With phosphorus; sulfur; at 133 - 152 ℃; for 1h; Yields of byproduct given. Title compound not separated from byproducts;

Reference yield: 2.6%

ortho-cresol (95-48-7,77504-84-8) → O,O,O-tri-o-tolyl phosphorothioate (631-45-8) + tetrakis(o-tolyloxy)diphosphine disulfide (73608-47-6)

Guidance literature:

With phosphorus; sulfur; at 185 - 235 ℃; for 11h;

upstream raw materials:

tri(O-methylphenyl)phosphite

ortho-cresol

Refernces

• 1、 Zhang, Yue,Cai, Ziman,Chi, Yangyang,Zeng, Xiangzhe,Chen, Shuanghui,Liu, Yan,Tang, Guo,Zhao, Yufen. "Diphenyl Diselenide-Catalyzed Synthesis of Triaryl Phosphites and Triaryl Phosphates from White Phosphorus". supporting information. p. 5158 - 5163. Retrieved 2021/07/20.
• 2、 Mazitova, F. N.,Khairullin, V. K.. "NEW METHOD FOR THE SYNTHESIS OF O,O-DIARYL HYDROGEN PHOSPHORODITHIOATES, O,O,O-TRIARYL PHOSPHOROTHIOATES, AND TETRAKIS(ARYLOXY)DIPHOSPHINE". . p. 652 - 658. Retrieved 2007/10/02.