4-Chloro-2-phenylazo-phenol

Base Information

• Chemical Name: 4-Chloro-2-phenylazo-phenol
• CAS No.: 21524-25-4
• Molecular Formula: C12H9ClN2O
• Molecular Weight: 232.669
• NSC Number: 85551
• ChEMBL ID: CHEMBL1500164
• Mol file: 21524-25-4.mol

Synonyms:4-Chloro-2-phenylazo-phenol;MLS001207205;SMR000517102;4-chloro-2-(phenyldiazenyl)phenol;21524-25-4;NSC85551;NCIOpen2_005021;CHEMBL1500164;BDBM76635;cid_5765348;HMS2823L11;(6E)-4-chloro-6-(phenylhydrazinylidene)cyclohexa-2,4-dien-1-one;NSC-85551;AKOS000715195;(6E)-4-chloro-6-(phenylhydrazono)cyclohexa-2,4-dien-1-one;(6E)-4-chloranyl-6-(phenylhydrazinylidene)cyclohexa-2,4-dien-1-one;(6E)-4-chloro-6-(phenylhydrazinylidene)-1-cyclohexa-2,4-dienone

Chemical Property of 4-Chloro-2-phenylazo-phenol

Chemical Property:

• Vapor Pressure: 0.0001mmHg at 25°C
• Boiling Point: 338.1°Cat760mmHg
• Flash Point: 158.3°C
• Density: 1.25g/cm³
• XLogP3: 4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 232.0403406
• Heavy Atom Count: 16
• Complexity: 241

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)N=NC2=C(C=CC(=C2)Cl)O

Technology Process of 4-Chloro-2-phenylazo-phenol

There total 6 articles about 4-Chloro-2-phenylazo-phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

4-chloro-phenol (106-48-9,82344-39-6) + aniline (62-53-3) → 2-hydroxy-5-chloroazobenzene (21524-25-4)

Guidance literature:

aniline; With silica gel; sodium nitrite; In water; for 0.25h;

4-chloro-phenol; With sodium hydroxide; In water;

DOI:10.1080/15533174.2011.555872

Reference yield:

4-chloro-phenol (106-48-9,82344-39-6) → 2-hydroxy-5-chloroazobenzene (21524-25-4)

Guidance literature:

With sodium hydroxide; ethanol; sodium carbonate; anschliessend mit Benzoldiazoniumchlorid;

DOI:10.1021/ja01107a511

Reference yield:

benzene diazonium chloride (100-34-5) + 4-chloro-phenol (106-48-9,82344-39-6) → 2-hydroxy-5-chloroazobenzene (21524-25-4)

Guidance literature:

With alkali;

upstream raw materials:

benzene diazonium chloride

4-chloro-phenol

benzenediazonium

aniline

Downstream raw materials:

2-hydroxy-5-chloro-aniline

(ClC₆H₃(O)N₂C₆H₅)2Cu

1-(5-chlorobenzo[d]oxazol-2-yl)guanidine

5-chlorobenzo[d]oxazole-2(3H)-thione

Refernces

• 1、 Jirandehi, Hasan Fathinejad,Mobinikhaledi, Akbar. "Synthesis of some aryl azo-compounds under mild conditions". experimental part. p. 6851 - 6854. Retrieved 2012/07/03.