Technology Process of 11-Fluoro-5-methylchrysene
There total 9 articles about 11-Fluoro-5-methylchrysene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
diethylamino-sulfur trifluoride;
In
dichloromethane;
DOI:10.1021/jm00199a007
- Guidance literature:
-
Multi-step reaction with 2 steps
1: (i) OsO4, Py, benzene, (ii) D-mannitol, aq. NaOH, CH2Cl2
2: Et2NSF3 / CH2Cl2
With
diethylamino-sulfur trifluoride;
In
dichloromethane;
DOI:10.1021/jm00199a007
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: diisobutylaluminium hydride / toluene / 1.5 h / -78 °C / Inert atmosphere
2.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / -95 °C / Inert atmosphere
2.2: -95 - -30 °C / Inert atmosphere
2.3: 1.5 h / -30 - 0 °C / Inert atmosphere
3.1: zinc / N,N-dimethyl-formamide / 2 h / 20 °C / Inert atmosphere
4.1: indium(III) bromide / 1,2-dichloro-ethane / 0.5 h / 20 °C / Inert atmosphere; Glovebox
5.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / 1,2-dichloro-ethane / 1.5 h / Inert atmosphere; Reflux; Glovebox
With
indium(III) bromide; diisobutylaluminium hydride; 2,3-dicyano-5,6-dichloro-p-benzoquinone; zinc; lithium diisopropyl amide;
In
tetrahydrofuran; 1,2-dichloro-ethane; N,N-dimethyl-formamide; toluene;
DOI:10.1002/anie.201302740
