2,6-Dichloro-9-thiabicyclo(3.3.1)nonane

Base Information

• Chemical Name: 2,6-Dichloro-9-thiabicyclo(3.3.1)nonane
• CAS No.: 6522-21-0
• Molecular Formula: C₈H₁₂Cl₂S
• Molecular Weight: 211.155
• Hs Code.: 2934999090
• Mol file: 6522-21-0.mol

Synonyms:2,6-dichloro-9-thiabicyclo[3.3.1]nonane;9-Thiabicyclo[3.3.1]nonane,2,6-dichloro;Wln: T66 A astj cg gg;endo,endo-2,6-Dichlor-9-thiabicyclo[3.3.1]nonan;

Chemical Property of 2,6-Dichloro-9-thiabicyclo(3.3.1)nonane

Chemical Property:

• Vapor Pressure: 0.000382mmHg at 25°C
• Boiling Point: 327.6°Cat760mmHg
• Flash Point: 144.3°C
• PSA: 25.30000
• Density: 1.29g/cm³
• LogP: 3.25920

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,6-Dichloro-9-thiabicyclo(3.3.1)nonane

There total 4 articles about 2,6-Dichloro-9-thiabicyclo(3.3.1)nonane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

1,5-cis,cis-cyclooctadiene (1552-12-1,111-78-4) → (+)-2,6-dichloro-9-thiabicyclo[3.3.1]nonane (6522-21-0)

Guidance literature:

In dichloromethane; at -50 - 20 ℃; for 6h; under Ar;

DOI:10.1007/BF02464354

Reference yield:

1,5-cis,cis-cyclooctadiene (1552-12-1,111-78-4) → endo,endo-2,6-Dichlor-9-thiabicyclo<3.3.1>nonan (6522-21-0,10502-30-4,14965-28-7)

Guidance literature:

1,5-cis,cis-cyclooctadiene; With sulfur monochloride; In dichloromethane; at 0 - 4 ℃; for 2.5h;

With sulfuryl dichloride; In dichloromethane; at 20 ℃; for 1.5h;

DOI:10.3390/11040212

Reference yield:

1,5-cis,cis-cyclooctadiene (1552-12-1,111-78-4) + thiocyanatochloride (5961-98-8) → endo,endo-2,6-Dichlor-9-thiabicyclo<3.3.1>nonan (6522-21-0,10502-30-4,14965-28-7) + trans-5-Chlor-6-thiocyanato-(Z)-cycloocten (79209-38-4) + endo,endo-2,6-Dithiocyanato-9-thiabicyclo<3.3.1>nonan (6522-29-8,79209-39-5)

Guidance literature:

In acetic acid; at 20 - 25 ℃; for 2h; Yields of byproduct given;

upstream raw materials:

1,5-cis,cis-cyclooctadiene

thiocyanatochloride

Downstream raw materials:

9-thia-bicyclo[3.3.1]nonane

2-isobutyl-9-thiabicyclo<3.3.1>nonane

2,6-diisobutyl-9-thiabicyclo<3.3.1>nonane

Refernces

• 1、 Lautenschlaeger. "". . p. 2813,2816. Retrieved 1966.
• 2、 Diaz, David Diaz,Converso, Antonella,Sharpless, K. Barry,Finn. "2,6-Dichloro-9-thiabicyclo[3.3.1]nonane: Multigram display of azide and cyanide components on a versatile scaffold". . p. 212 - 218. Retrieved 2007/10/03.