(2Z)-2-[(4-chlorophenyl)hydrazono]-3-oxo-3-phenylpropanal

Base Information

• Chemical Name: (2Z)-2-[(4-chlorophenyl)hydrazono]-3-oxo-3-phenylpropanal
• CAS No.: 40640-21-9
• Molecular Formula: C15H11ClN2O2
• Molecular Weight: 286.718
• Mol file: 40640-21-9.mol

Synonyms:

Chemical Property of (2Z)-2-[(4-chlorophenyl)hydrazono]-3-oxo-3-phenylpropanal

Chemical Property:

• Vapor Pressure: 1.01E-07mmHg at 25°C
• Boiling Point: 433.7°Cat760mmHg
• Flash Point: 216.1°C
• Density: 1.24g/cm³

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2Z)-2-[(4-chlorophenyl)hydrazono]-3-oxo-3-phenylpropanal

There total 3 articles about (2Z)-2-[(4-chlorophenyl)hydrazono]-3-oxo-3-phenylpropanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

2-(2-p-chlorophenylhydrazono)-3-hydroxy-1-phenylpropan-1-one → 2-(2-p-chlorophenylhydrazono)-3-oxo-3-phenylpropanal (40640-21-9)

Guidance literature:

With nitrobenzene; for 2h; Reflux;

DOI:10.3998/ark.5550190.0012.225

Reference yield:

3-oxo-3-phenylpropionic acid (614-20-0) → 2-(2-p-chlorophenylhydrazono)-3-oxo-3-phenylpropanal (40640-21-9)

Guidance literature:

Multi-step reaction with 3 steps

1: water / 2 h / 0 - 5 °C

2: montmorillonite K₁₀ / methanol; water / 2 h / Reflux

3: nitrobenzene / 2 h / Reflux

With nitrobenzene; In methanol; water;

DOI:10.3998/ark.5550190.0012.225

Reference yield:

ethyl 3-oxo-3-phenylpropionate (94-02-0) → 2-(2-p-chlorophenylhydrazono)-3-oxo-3-phenylpropanal (40640-21-9)

Guidance literature:

Multi-step reaction with 4 steps

1.1: water; potassium hydroxide / 24 h / 20 °C

1.2: 0 - 5 °C

2.1: water / 2 h / 0 - 5 °C

3.1: montmorillonite K₁₀ / methanol; water / 2 h / Reflux

4.1: nitrobenzene / 2 h / Reflux

With water; nitrobenzene; potassium hydroxide; In methanol; water;

DOI:10.3998/ark.5550190.0012.225

upstream raw materials:

3-oxo-3-phenylpropionic acid

ethyl 3-oxo-3-phenylpropionate

Refernces