METHOXYALLENE; 95%DISCONTINUED 05/24/01

Base Information

• Chemical Name: METHOXYALLENE; 95%DISCONTINUED 05/24/01
• CAS No.: 13169-00-1
• Molecular Formula: C4H6O
• Molecular Weight: 70.091
• Hs Code.: 2909199090
• Mol file: 13169-00-1.mol

Synonyms:Methyl propadienyl ether;NSC 363923;Ether,methyl propadienyl (8CI);1-Methoxy-1,2-propadiene;1-Methoxyallene;1-Methoxypropadiene;Allenyl methyl ether;Methoxyallene;Methoxypropadiene;

Chemical Property of METHOXYALLENE; 95%DISCONTINUED 05/24/01

Chemical Property:

• Appearance/Colour: UN 1993
• Refractive Index: n20/D 1.429
• Boiling Point: 48.2 °C at 760 mmHg
• Flash Point: -29 °C
• PSA: 9.23000
• Density: 0.74 g/cm³
• LogP: 0.93140
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

Methoxyallene technical grade ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F
• Hazard Codes: F
• Statements: 11

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Reactant involved in:? ;Multicomponent reactions with nitriles and carboxylic acids followed by cyclocondensation for synthesis of enantiopure pyridines1? ;Intermolecular hydroamination2? ;One-pot synthesis of alkoxy and (alkylsulfanyl)-substituted pyrroles and dihydropyridines3? ;Intermolecular [4+2] cycloaddition with dienes4? ;Allenyl cyclization and subsequent transformation into dicarbonyl, cyclopentenones, and butenolide compounds5? ;Insertion reactions of C-C pi-bonds into alkylidenesilacyclopropanes6 Reactant involved in:Multicomponent reactions with nitriles and carboxylic acids followed by cyclocondensation for synthesis of enantiopure pyridinesIntermolecular hydroaminationOne-pot synthesis of alkoxy and (alkylsulfanyl)-substituted pyrroles and dihydropyridinesIntermolecular [4+2] cycloaddition with dienesAllenyl cyclization and subsequent transformation into dicarbonyl, cyclopentenones, and butenolide compoundsInsertion reactions of C-C pi-bonds into alkylidenesilacyclopropanes

Technology Process of METHOXYALLENE; 95%DISCONTINUED 05/24/01

There total 10 articles about METHOXYALLENE; 95%DISCONTINUED 05/24/01 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

propargyl alcohol methyl ether (627-41-8) → Methoxyallene (13169-00-1)

Guidance literature:

With potassium tert-butylate; for 1h; Heating / reflux;

Reference yield: 91.0%

ethynyl methyl ether (6443-91-0) → Methoxyallene (13169-00-1)

Guidance literature:

With potassium tert-butylate; for 3h; Heating / reflux;

Reference yield: 91.0%

methylallylether (627-40-7) → Methoxyallene (13169-00-1)

Guidance literature:

With potassium tert-butylate; for 3h; Heating;

DOI:10.1016/j.jorganchem.2003.06.001

upstream raw materials:

propargyl alcohol methyl ether

methylallylether

potassium tert-butylate

ethynyl methyl ether

Downstream raw materials:

3,9-bis-(4-chloro-phenyl)-6-methoxy-1,7-dioxa-2,8-diaza-spiro[4.4]nona-2,8-diene

3-(4-chloro-phenyl)-4-(E)-methoxymethylene-4,5-dihydro-isoxazole

3-(4-chloro-phenyl)-4-(Z)-methoxymethylene-4,5-dihydro-isoxazole

2-methoxy-3-(1'-methoxy-2'-p-tolylthioprop-2'-enyl)oxane

Refernces

• 1、 Seghers, Sofie,Heugebaert, Thomas S. A.,Moens, Matthias,Sonck, Jolien,Thybaut, Joris W.,Stevens, Christian V.. "Design of a mesoscale continuous-flow route toward lithiated methoxyallene". . p. , 2248. Retrieved 2018/10/20.
• 2、 De la Campa, Raquel,Flrez, Josefa. "Water freezing as a regiocontrol element in the multicomponent assembly of cyclic enones". supporting information. p. 1854 - 1859. Retrieved 2015/01/30.