Pridinol methanesulfonate

Base Information

• Chemical Name: Pridinol methanesulfonate
• CAS No.: 6856-31-1
• Molecular Formula: C21H29NO4S
• Molecular Weight: 391.5243
• European Community (EC) Number: 229-953-2
• NSC Number: 758235
• UNII: AQ4K0AJT6G
• DSSTox Substance ID: DTXSID40218667
• Wikidata: Q27274059
• ChEMBL ID: CHEMBL1528011
• Mol file: 6856-31-1.mol

Synonyms:3-(N-piperidinyl)-1,1-diphenyl-1-propanol methanesulfonate;3-piperidino-1,1-diphenylpropanol;3-piperidinyl-1,1-diphenylpropan-1-ol;Myoson;pridinol;pridinol mesylate;pridinol monohydrochloride;pridinol monomesylate;ridinol

Chemical Property of Pridinol methanesulfonate

Chemical Property:

• Appearance/Colour: White to Off-White Crystalline Powder
• Melting Point: 152.5-155 °C
• Boiling Point: 585.1 °C at 760 mmHg
• Flash Point: 307.6 °C
• PSA: 86.22000
• LogP: 4.32120
• Storage Temp.: 2-8°C
• Solubility.: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly), Water (Spa
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 391.18172958
• Heavy Atom Count: 27
• Complexity: 386

Purity/Quality:

98%,99%, ^*data from raw suppliers

Pridinol methanesulfonate salt ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 20/21/22
• Safety Statements: 36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CS(=O)(=O)O.C1CCN(CC1)CCC(C2=CC=CC=C2)(C3=CC=CC=C3)O
• Uses: Pridinol Methanesulfonate Salt can be used as an antiparkinsonian agent and as an anticholinergic.

Technology Process of Pridinol methanesulfonate

There total 2 articles about Pridinol methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.08%

methanesulfonic acid (75-75-2,98527-29-8) + Pridinol (511-45-5) → pridinol methanesulfonate (6856-31-1)

Guidance literature:

In diethyl ether; at -15 ℃; Solvent; Temperature;

Reference yield:

piperidine (110-89-4) → pridinol methanesulfonate (6856-31-1)

Guidance literature:

Multi-step reaction with 3 steps

1.1: 110 °C / Reflux; Large scale

2.1: tetrahydrofuran / 3 h / 0 - 66 °C

2.2: 0 °C

3.1: diethyl ether / -15 °C

In tetrahydrofuran; diethyl ether;

upstream raw materials:

piperidine

methanesulfonic acid

Pridinol

Refernces