5-hydroxyoctanoic acid

Base Information

• Chemical Name: 5-hydroxyoctanoic acid
• CAS No.: 29671-57-6
• Molecular Formula: C₈H₁₆O₃
• Molecular Weight: 160.213
• Hs Code.: 2918199090
• Mol file: 29671-57-6.mol

Synonyms:2-Ethyl-3-hydroxyhexanoicacid

Chemical Property of 5-hydroxyoctanoic acid

Chemical Property:

• Vapor Pressure: 0.000214mmHg at 25°C
• Boiling Point: 291.2°Cat760mmHg
• Flash Point: 144.1°C
• PSA: 57.53000
• Density: 1.046g/cm³
• LogP: 1.25820

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-hydroxyoctanoic acid

There total 3 articles about 5-hydroxyoctanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

2-ethyl-1,3-hexane diol (94-96-2,1321-34-2) → 2-ethyl-1-hydroxy-3-hexanone (27970-80-5) + 2-ethyl-3-hydroxy-hexanoic acid (29671-57-6) + 2-ethyl-3-oxohexanoic acid (4384-00-3)

Guidance literature:

With 2-Picolinic acid; manganese(II) perchlorate hexahydrate; dihydrogen peroxide; sodium acetate; In acetonitrile; at 0 - 20 ℃; chemoselective reaction;

DOI:10.1002/cssc.201300378

Reference yield:

2-ethyl-3-hydroxy-hexanoic acid-(2-ethyl-3-hydroxy-hexyl ester) (60701-84-0) → 2-ethyl-3-hydroxy-hexanoic acid (29671-57-6)

Guidance literature:

With potassium hydroxide;

DOI:10.1002/hlca.19510340710

Reference yield:

→ 2-ethyl-3-hydroxy-hexanoic acid (29671-57-6)

Guidance literature:

With potassium hydroxide;

upstream raw materials:

2-ethyl-3-hydroxy-hexanoic acid-(2-ethyl-3-hydroxy-hexyl ester)

2-ethyl-1,3-hexane diol

Refernces