18-hydroxy-11-dehydrotetrahydrocorticosterone

Base Information

• Chemical Name: 18-hydroxy-11-dehydrotetrahydrocorticosterone
• CAS No.: 7050-24-0
• Molecular Formula: C₂₁H₃₂O₅
• Molecular Weight: 364.482
• Mol file: 7050-24-0.mol

Synonyms:5b-Pregnane-11,20-dione, 3a,18,21-trihydroxy- (8CI); 3a,18,21-Trihydroxy-5b-pregnane-11,20-dione

Chemical Property of 18-hydroxy-11-dehydrotetrahydrocorticosterone

Chemical Property:

• Vapor Pressure: 1.21E-14mmHg at 25°C
• Boiling Point: 555.3°C at 760 mmHg
• Flash Point: 303.7°C
• PSA: 0.00000
• Density: 1.235g/cm³
• LogP: 0.00000

Purity/Quality:

HPLC ≥ 98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: (3α,5β)-3,18,21-Trihydroxypregnane-11,20-dione, is a derivative of Tetrahydrodehydrocor?ticosterone (T293165), that inhibits aldosteronogenesis by intact cells at concentrations that inhibited angiotensin binding.

Technology Process of 18-hydroxy-11-dehydrotetrahydrocorticosterone

There total 1 articles about 18-hydroxy-11-dehydrotetrahydrocorticosterone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3α,18,21-Trihydroxy-11,20-dioxo-pregnan (7050-24-0,10456-49-2)

Guidance literature:

Diese Struktur entsteht nicht, wie frueher berichtet (Ulick et al., Am.Soc. 79 <1957> 6567) beim Stoffwechsel v. Aldosteron i. Harn, sondern beim Stoffwechsel v. 18-Hydroxy-corticosteron.;

DOI:10.1021/ja01482a054