(4R)-4-[[(3S,6R,9S,12R,15S,18R,21R,22R)-3-[(2S)-butan-2-yl]-6,12-bis(h ydroxymethyl)-22-methyl-9,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-hep taoxo-18-propan-2-yl-1-oxa-4,7,10,13,16,19-hexazacyclodocos-21-yl]carb amoyl]-4-[[(2S)-2-[[(3R)-3-hydroxydecanoyl]amino]-4-methyl-pentanoyl]a mino]butanoic acid

Base Information

• Chemical Name: (4R)-4-[[(3S,6R,9S,12R,15S,18R,21R,22R)-3-[(2S)-butan-2-yl]-6,12-bis(h ydroxymethyl)-22-methyl-9,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-hep taoxo-18-propan-2-yl-1-oxa-4,7,10,13,16,19-hexazacyclodocos-21-yl]carb amoyl]-4-[[(2S)-2-[[(3R)-3-hydroxydecanoyl]amino]-4-methyl-pentanoyl]a mino]butanoic acid
• CAS No.: 27127-62-4
• Molecular Formula: C₅₄H₉₅N₉O₁₆
• Molecular Weight: 1126.4
• Mol file: 27127-62-4.mol

Synonyms:1-Oxa-4,7,10,13,16,19-hexaazacyclodocosane,cyclic peptide deriv.; L-Isoleucine,N-[N-[N-[N-[N-[N-[N-[N-[N-[(R)-3-hydroxy-1-oxodecyl]-L-leucyl]-D-a-glutamyl]-D-allothreonyl]-D-valyl]-L-leucyl]-D-seryl]-L-leucyl]-D-seryl]-,u-lactone;N-[N-[N-[N-[N-[N-[N-[N-[N-[(R)-3-Hydroxy-1-oxodecyl]-L-leucyl]-D-a-glutamyl]-D-allothreonyl]-D-valyl]-L-leucyl]-D-seryl]-L-leucyl]-D-seryl]-L-isoleucineu-lactone

Chemical Property of (4R)-4-[[(3S,6R,9S,12R,15S,18R,21R,22R)-3-[(2S)-butan-2-yl]-6,12-bis(h ydroxymethyl)-22-methyl-9,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-hep taoxo-18-propan-2-yl-1-oxa-4,7,10,13,16,19-hexazacyclodocos-21-yl]carb amoyl]-4-[[(2S)-2-[[(3R)-3-hydroxydecanoyl]amino]-4-methyl-pentanoyl]a mino]butanoic acid

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 294-295 °C (decomp)
• Boiling Point: 1431.2°Cat760mmHg
• PKA: 4.43±0.10(Predicted)
• Flash Point: 819.3°C
• PSA: 386.19000
• Density: 1.22g/cm³
• LogP: 3.24170

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4R)-4-[[(3S,6R,9S,12R,15S,18R,21R,22R)-3-[(2S)-butan-2-yl]-6,12-bis(h ydroxymethyl)-22-methyl-9,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-hep taoxo-18-propan-2-yl-1-oxa-4,7,10,13,16,19-hexazacyclodocos-21-yl]carb amoyl]-4-[[(2S)-2-[[(3R)-3-hydroxydecanoyl]amino]-4-methyl-pentanoyl]a mino]butanoic acid

There total 1 articles about (4R)-4-[[(3S,6R,9S,12R,15S,18R,21R,22R)-3-[(2S)-butan-2-yl]-6,12-bis(h ydroxymethyl)-22-methyl-9,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-hep taoxo-18-propan-2-yl-1-oxa-4,7,10,13,16,19-hexazacyclodocos-21-yl]carb amoyl]-4-[[(2S)-2-[[(3R)-3-hydroxydecanoyl]amino]-4-methyl-pentanoyl]a mino]butanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

C75H113N9O16 (122889-10-5) → viscosin (27127-62-4,135096-89-8)

Guidance literature:

With ammonium formate; palladium on activated charcoal; In methanol;

DOI:10.1016/S0040-4039(00)95242-0

upstream raw materials:

C₇₅H₁₁₃N₉O₁₆

Refernces