Canthaxanthin

Base Information

• Chemical Name: Canthaxanthin
• CAS No.: 514-78-3
• Molecular Formula: C40H52O2
• Molecular Weight: 564.852
• Hs Code.: 3204199000
• Mol file: 514-78-3.mol

Synonyms:b-Carotene-4,4'-dione (6CI);b-Carotene-4,4'-dione, all-trans-(8CI);4,4'-Diketo-b-carotene;4,4'-Dioxo-b-carotene;C.I. 40850;C.I. Food Orange 8;Carophyll red;E 161g;Food Orange 8;Lucantin Red;NSC 374110;Roxanthin Red10;all-trans-Canthaxanthin;

Chemical Property of Canthaxanthin

Chemical Property:

• Appearance/Colour: purple to reddish-violet
• Vapor Pressure: 2.09E-20mmHg at 25°C
• Melting Point: 217～218℃
• Refractive Index: 1.575
• Boiling Point: 717 °C at 760 mmHg
• Flash Point: 253.9 °C
• PSA: 34.14000
• Density: 1.003 g/cm³
• LogP: 10.96380
• Storage Temp.: 0-6°C
• Solubility.: Chloroform (Slightly)

Purity/Quality:

99%, ^*data from raw suppliers

all-trans-Canthaxanthin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: Oral suntanning agent Antioxidant immune to promote Permissible color additive for food and drugs (exempt from certification): Fed. Regist. 34, no. 5 (Jan. 8, 1969). Oral suntanning agent. Canthaxanthin is a synthetic red colorant that is the carotenoid of most intense red color. it is available in oil-soluble, oil-dispersible, and water-dispersible forms. it has fair ph, heat, light, and chemical stability with a low tinctorial strength. unlike the carotenoids beta- carotene and beta-apo-8-carotenal, it does not possess vitamin a activity. maximum usage level is 66 ppm. uses include carbonated soft drinks, salad dressing, and spaghetti sauce.

Technology Process of Canthaxanthin

There total 54 articles about Canthaxanthin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.5%

beta-carotene (7235-40-7) → canthaxanthin (514-78-3)

Guidance literature:

With cerium(IV) oxide; sulfuric acid; potassium iodide; In dichloromethane; water; at 0 ℃; for 2.5h; under 760.051 Torr; Reagent/catalyst; Temperature; UV-irradiation;

Reference yield: 94.66%

β-carotene (161023-01-4) → canthaxanthin (514-78-3)

Guidance literature:

With Aminoiminomethanesulfinic acid; In dichloromethane; water; at 20 - 40 ℃; for 17h; Temperature; Industrial scale;

Reference yield: 92.1%

(2E,4E,6E)-2,7-dimethyl-2,4,6-octatrienedial (5056-17-7) + C19H31O4P → canthaxanthin (514-78-3)

Guidance literature:

With sodium t-butanolate; In dimethyl sulfoxide; toluene; at -20 ℃; for 6h; Reagent/catalyst; Temperature; Solvent;

upstream raw materials:

N-Bromosuccinimide

4-Phenylmorpholine

ethanol

chloroform

Downstream raw materials:

isozeaxanthin

6,5'-retro-5,6-dihydro-β,β-carotene-4,4'-dione

C₄₀H₅₂O₂⁽²⁺⁾

C₄₀H₅₂O₂⁽¹⁺⁾

Refernces

• 1、 -. "Synthesis method of canthaxanthin". Paragraph 0043-0058. . Retrieved 2020/07/28.
• 2、 -. "Method for preparing cyclic alpha, beta-unsaturated ketone". Paragraph 0056-0057. . Retrieved 2020/07/13.