Technology Process of Cyclooctyl 2-methylpropanoate
There total 5 articles about Cyclooctyl 2-methylpropanoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
cyclooctanol;
With
triethylamine;
In
dichloromethane;
at 0 ℃;
for 0.0833333h;
isobutyryl chloride;
In
dichloromethane;
at 0 - 20 ℃;
for 3h;
DOI:10.1039/c9cc02060h
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1) bromomagnesium diisopropylamide; 2) methyl iodide, 15 percent HCl / 1) -40 deg C, ether, 2 h; 2) benzene, reflux, 2 h; RT, 15 min
2: DMAP / pyridine
With
hydrogenchloride; dmap; bromomagnesium diisopropylamide; methyl iodide;
In
pyridine;
DOI:10.1016/S0040-4020(01)88162-X
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1) LDA; 2) methyl iodide, 15 percent HCl / 1) THF, -78 deg C; 2) THF, reflux 2 h; RT, 15 min
2: DMAP / pyridine
With
hydrogenchloride; dmap; lithium diisopropyl amide; methyl iodide;
In
pyridine;
DOI:10.1016/S0040-4020(01)88162-X
