Ethyl methacrylate

Base Information

• Chemical Name: Ethyl methacrylate
• CAS No.: 97-63-2
• Molecular Formula: C6H10O2
• Molecular Weight: 114.144
• Hs Code.: 2916140000
• European Community (EC) Number: 202-597-5
• ICSC Number: 0272
• NSC Number: 24152
• UN Number: 2277
• UNII: 80F70CLT4O
• DSSTox Substance ID: DTXSID1025308
• Nikkaji Number: J3.576I
• Wikipedia: Ethyl_methacrylate
• Wikidata: Q424811
• ChEMBL ID: CHEMBL3182984
• Mol file: 97-63-2.mol

Synonyms:ethyl methacrylate monomer

Chemical Property of Ethyl methacrylate

Chemical Property:

• Appearance/Colour: colourless liquid with an unpleasant odour
• Vapor Pressure: 4.84mmHg at 25°C
• Melting Point: -75 °C
• Refractive Index: n20/D 1.413(lit.)
• Boiling Point: 120.5 °C at 760 mmHg
• Flash Point: 15.6 °C
• PSA: 26.30000
• Density: 0.906 g/cm³
• LogP: 1.12560
• Water Solubility.: 4 g/L (20℃)
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 114.068079557
• Heavy Atom Count: 8
• Complexity: 105
• Transport DOT Label: Flammable Liquid

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s): F,Xi
• Hazard Codes: F:Flammable;;
• Statements: R11:; R36/37/38:; R43:
• Safety Statements: S16:; S29:; S33:; S9:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Plastics & Rubber -> (Meth)acrylates
• Canonical SMILES: CCOC(=O)C(=C)C
• Inhalation Risk: No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C.
• Effects of Short Term Exposure: Lachrymation. The substance is irritating to the eyes, skin and respiratory tract.
• Effects of Long Term Exposure: Repeated or prolonged contact may cause skin sensitization.

Technology Process of Ethyl methacrylate

There total 50 articles about Ethyl methacrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

2-methyl-2-propenoic acid 2-hydroxyethyl ester (868-77-9,141668-69-1,25736-86-1,82601-55-6,25249-16-5) → 2,3-dioxycarbonylpropyl (ethyl methacrylate) carbonate + methyl methacrylate (97-63-2,9003-42-3)

Guidance literature:

With pyridine; In dichloromethane; water;

Reference yield: 71.0%

ethanol (64-17-5) + 1,2-propanediene (463-49-0) + carbon monoxide (201230-82-2) → methyl methacrylate (97-63-2,9003-42-3)

Guidance literature:

dodecacarbonyl-triangulo-triruthenium; at 100 ℃; for 3h; under 11400 Torr;

DOI:10.1039/b205817k

Reference yield: 60.0%

β-acetoxy-isobutyric acid ethyl ester (88226-62-4) → methyl methacrylate (97-63-2,9003-42-3)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In benzene; at 80 ℃; for 5h;

DOI:10.1016/S0040-4039(00)86017-7

upstream raw materials:

ethyl 2-bromoisobutyrate

formaldehyd

monoethyl methylmalonate

ethyl 2-ethoxy-2-methylpropanoate

Downstream raw materials:

3-ethyl-2-methylpent-1-en-3-ol

2,3-dimethyl-1-buten-3-ol

2,3-dimethyl-buta-1,3-diene

3-methyl-pentan-2-one

Refernces

• 1、 Koyama, Minoru,Kawakami, Takafumi,Okazoe, Takashi,Nozaki, Kyoko. "Cyanide-Free One-Pot Synthesis of Methacrylic Esters from Acetone". . p. 10913 - 10917. Retrieved 2019/08/02.
• 2、 Munyemana, Fran?ois,George, Isabelle,Devos, Alain,Colens, Alain,Badarau, Eduard,Frisque-Hesbain, Anne-Marie,Loudet, Aurore,Differding, Edmond,Damien, Jean-Marie,Rémion, Jeanine,Van Uytbergen, Jacqueline,Ghosez, Léon. "A mild method for the replacement of a hydroxyl group by halogen. 1. Scope and chemoselectivity". . p. 420 - 430. Retrieved 2015/12/31.