2-Hydrazinobenzoic acid

Base Information

• Chemical Name: 2-Hydrazinobenzoic acid
• CAS No.: 5326-27-2
• Molecular Formula: C7H8N2O2
• Molecular Weight: 152.153
• Hs Code.: 2916399090
• European Community (EC) Number: 226-202-0
• NSC Number: 282
• UNII: WDR9R94GA3
• DSSTox Substance ID: DTXSID40201377
• Nikkaji Number: J26.921B
• Wikidata: Q83074589
• Mol file: 5326-27-2.mol

Synonyms:2-Hydrazinobenzoic acid;5326-27-2;2-hydrazinylbenzoic acid;Benzoic acid, hydrazino-;o-Hydrazinobenzoic acid;2-Hydrazino-benzoic acid;Benzoic acid, 2-hydrazino-;WDR9R94GA3;NSC-282;EINECS 226-202-0;2-hydrazinobenzoicacid;hydrazinobenzoic acid;2-diazanylbenzoic acid;starbld0018246;2-hydrazino benzoic acid;2-hydrazinyl-benzoic acid;UNII-WDR9R94GA3;Oprea1_390074;SCHEMBL143766;NSC282;DTXSID40201377;NSC 282;BENZOIC ACID, O-HYDRAZINO-;BENZOIC ACID, 2-HYDRAZINYL-;BBL019027;STK501160;AKOS000321276;SB75713;AMY202100095;VS-06867;BB 0240625;FT-0612512;A829480;F8880-0923

Chemical Property of 2-Hydrazinobenzoic acid

Chemical Property:

• Melting Point: 247 °C
• Boiling Point: 352.3 °C at 760 mmHg
• PKA: 3.30±0.36(Predicted)
• Flash Point: 166.9 °C
• PSA: 75.35000
• Density: 1.401g/cm³
• LogP: 1.44370
• XLogP3: -1
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 152.058577502
• Heavy Atom Count: 11
• Complexity: 149

Purity/Quality:

98%min ^*data from raw suppliers

2-HydrazinylbenzoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)C(=O)O)NN

Technology Process of 2-Hydrazinobenzoic acid

There total 3 articles about 2-Hydrazinobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

→ 2-hydrazino-benzoic acid (5326-27-2)

Guidance literature:

Reference yield:

5,6,7,12,13,14-hexahydrodibenzo<1,2,6,7>tetrazecine-7,14-dione (93293-17-5) → 2-hydrazino-benzoic acid (5326-27-2)

Guidance literature:

With hydrogenchloride; for 12h; Heating;

Reference yield:

→ 2-hydrazino-benzoic acid (5326-27-2)

Guidance literature:

Reaktion ueber mehrere Stufen;

DOI:10.1016/S0272-6386(00)70039-4

upstream raw materials:

5,6,7,12,13,14-hexahydrodibenzo<1,2,6,7>tetrazecine-7,14-dione

Downstream raw materials:

o-(N-ethanoylhydrazino)benzoic acid

2-(N',N'-diacetyl-hydrazino)-benzoic acid

1,2-Diacetyl-1,2-dihydro-3H-indazol-3-one

1-(2-Carboxy-phenyl)-2-tosyl-hydrazin

Refernces

• 1、 Palat, Karel,Vontor, Tomas,Celadnik, Milan,Hanus, Vladimir. "PREPARATION OF A PARTIALLY HYDROGENATED DIBENZOTETRAZECINE AND ITS PYRIDINE ANALOGUE". . p. 1409 - 1411. Retrieved 2007/10/02.