Chemical Property of Acemannan
Edit
Chemical Property:
- Vapor Pressure:0mmHg at 25°C
- Boiling Point:1521.1°Cat760mmHg
- Flash Point:873.8°C
- PSA：732.86000
- Density:g/cm3
- LogP:-13.82940
- Purity/Quality:
-
99% *data from raw suppliers
Acemannan(TechnicalGrade) *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
-
SDS file from LookChem
Useful:
-
Description
Acemannan Hydrogel was marketed in the US as a wound healing agent for the care of
ulcers, burns and post-surgical incisions. Acemannan is a complex water soluble polymanno-
galacto acetate isolated from Aloe vera by alcohol precipitation and purified by
filtration to limit the size of the polysaccharide polymers. Pharmacological studies
demonstrated immunostimulatory activity through the activation of monocytes and
macrophages triggering enhanced secretion of cytokines such as interferon, interleukins,
TNF-alpha, GM-CSF and some prostaglandins. It was proposed that the adjuvant activity
of this agent could be partly related to its ability to induce phenotypic and functional
maturation of immature dendritic cells. In normal healthy males, acemannan administered
orally up to 3200 mg/day for 6 days did not show any acute oral toxicity. Acemannan is
currently undergoing clinical trials for the treatment of AIDS.
-
Uses
Antiviral; immunomodulator. Acemannan is an polysaccharide found in the leaves of Aloe Vera (Aloe barbadensis Miller) plant, and is used in a variety of Aloe Vera products.
