1,2-Difluoroethane

Base Information

• Chemical Name: 1,2-Difluoroethane
• CAS No.: 624-72-6
• Molecular Formula: C2H4 F2
• Molecular Weight: 66.0506
• Hs Code.: 2903399090
• European Community (EC) Number: 824-248-1
• UNII: 2IQ22ABI8P
• DSSTox Substance ID: DTXSID3073214
• Nikkaji Number: J6.853E
• Wikipedia: 1,2-Difluoroethane
• Wikidata: Q27254799
• Mol file: 624-72-6.mol

Synonyms:1,2-DIFLUOROETHANE;624-72-6;Ethylene difluoride;Freon 152;Ethane, 1,2-Difluoro-;Ethylene difluolride;HSDB 6786;UNII-2IQ22ABI8P;BRN 1730859;2IQ22ABI8P;4-01-00-00121 (Beilstein Handbook Reference);Fluorocarbon fc143;1,2-difluoro-ethane;CH2FCH2F;1,2-bis(fluoranyl)ethane;DTXSID3073214;HFC-152;FC143;1,2-DIFLUOROETHANE [HSDB];MFCD00039286;AKOS006229046;LS-65503;FT-0606119;FT-0606398;A833791;Q27254799

Chemical Property of 1,2-Difluoroethane

Chemical Property:

• Vapor Pressure: 1470mmHg at 25°C
• Melting Point: -118.59°C (estimate)
• Refractive Index: 1.2800
• Boiling Point: 31ºC
• PSA: 0.00000
• Density: 0,913 g/cm³
• LogP: 0.92540
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 66.02810645
• Heavy Atom Count: 4
• Complexity: 6

Purity/Quality:

99% ^*data from raw suppliers

1,2-Difluoroethane 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): TF
• Hazard Codes: F,T
• Statements: 12
• Safety Statements: 3/7-9-16-33

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Solvents -> Chlorofluorocarbons
• Canonical SMILES: C(CF)F

Technology Process of 1,2-Difluoroethane

There total 16 articles about 1,2-Difluoroethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

ethene (74-85-1) → 1,1-difluoroethane (75-37-6) + 1,2-difluoroethane (624-72-6) + 1,1,2-Trifluoroethan (430-66-0)

Guidance literature:

With xenon difluoride; silicon tetrafluoride; at 20 ℃; for 24h;

DOI:10.1002/(sici)1099-0690(199911)1999:11<3151::aid-ejoc3151>3.0.co;2-f

Reference yield: 20.0%

ethylene glycol (107-21-1) → ethylene sulfite (3741-38-6) + 1,2-difluoroethane (624-72-6)

Guidance literature:

With 4,4'-diaminostilbene-2,2'-disulfonic acid; In diethylene glycol dimethyl ether; for 0.5h; Yields of byproduct given;

Reference yield: 20.0%

trimethyleneglycol (504-63-2) → ethylene sulfite (3741-38-6) + 1,2-difluoroethane (624-72-6)

Guidance literature:

With 4,4'-diaminostilbene-2,2'-disulfonic acid; In 1,2-dimethoxyethane; for 0.5h; Mechanism; other diols, var. solv.;

upstream raw materials:

1-fluoro-2-propanone

1,3-difluoro-propan-2-one

1-(p-cyanophenyl)-3-(2-fluoroethyl)triazene

5-<3-(2-fluoroethyl)-1-triazenyl>-imidazole-4-carboxamide

Downstream raw materials:

1,2-difluoro-1,2-dichloroethene

1,2,2-trichloro-1,2-difluoroethane

CFC-112a

1-Chloro-1,2-difluoroethane

Refernces

• 1、 -. "METHOD FOR PRODUCING 1-CHLORO-1,2-DIFLUOROETHYLENE". Paragraph 0114. . Retrieved 2019/06/17.
• 2、 Misochko, Eugenii Ya.,Benderskii, Alexander V.,Wight, Charles A.. "Formation of β-Fluoroethyl Radical and Closed-Shell Products in Reactions of Photogenerated Fluorine Atoms with Ethene in Solid Argon". . p. 4496 - 4502. Retrieved 2007/10/03.