Ethyl-p-((E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propenyl)benzoate

Base Information Edit

Chemical Name:Ethyl-p-((E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propenyl)benzoate
CAS No.:71441-09-3
Molecular Formula:C26H32 O2
Molecular Weight:376.539
Hs Code.:
Nikkaji Number:J351.584B
Wikidata:Q76386406
ChEMBL ID:CHEMBL22369
Mol file:71441-09-3.mol

Synonyms:arotinoid ethyl ester;arotinoid Ro 136298;ethyl-p-((E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propenyl)benzoic acid;ethyl-p-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propenyl)benzoate;Ro 13-6298

Suppliers and Price of Ethyl-p-((E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propenyl)benzoate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
ArotinoidEthylEster
25mg
$ 165.00

American Custom Chemicals Corporation
ETHYL-PARA-((E)-2-(5,6,7,8-TETRAHYDRO-5,5,8,8-TETRAMETHYL-2-NAPHTHYL)-1-PROPENYL)BENZOIC ACID 95.00%
5MG
$ 495.18

Total 2 raw suppliers

Chemical Property of Ethyl-p-((E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propenyl)benzoate Edit

Chemical Property:

Vapor Pressure:1.86E-09mmHg at 25°C
Refractive Index:1.4480 (estimate)
Boiling Point:482.2°C at 760 mmHg
Flash Point:172.2°C
PSA：26.30000
Density:1.016g/cm³
LogP:6.77280
XLogP3:8.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:376.240230259
Heavy Atom Count:28
Complexity:577

Purity/Quality:

99% ^*data from raw suppliers

ArotinoidEthylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC=C(C=C1)C=C(C)C2=CC3=C(C=C2)C(CCC3(C)C)(C)C
Isomeric SMILES:CCOC(=O)C1=CC=C(C=C1)/C=C(\C)/C2=CC3=C(C=C2)C(CCC3(C)C)(C)C
Uses Arotinoid ethyl ester is a retinoid with a similar structure to vitamin A (R252000), and inhibits human epidermal keratinocyte RNase P activity, as well as tRNA biogenesis.

Technology Process of Ethyl-p-((E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propenyl)benzoate

There total 10 articles about Ethyl-p-((E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propenyl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 141-52-6
sodium ethanolate

: 71441-09-3
AGN 190316

Guidance literature:: diethyl p-carboxyethylbenzylphosphonate; With dimsylsodium; for 0.5h;

1-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphth-2-yl)ethanone; In dimethyl sulfoxide; for 4h;

sodium ethanolate; In ethanol; dimethyl sulfoxide;