1-Hexacosanol

Base Information

• Chemical Name: 1-Hexacosanol
• CAS No.: 506-52-5
• Molecular Formula: C26H54O
• Molecular Weight: 382.714
• Hs Code.: 2905199095
• European Community (EC) Number: 208-044-4
• NSC Number: 4058
• UNII: M7SD300NNB
• DSSTox Substance ID: DTXSID3027162
• Nikkaji Number: J6.230H
• Wikipedia: 1-Hexacosanol
• Wikidata: Q4545790
• Metabolomics Workbench ID: 3097
• Mol file: 506-52-5.mol

Synonyms:1-hexacosanol;1-hexacosanol, aluminum (1:3) salt;hexacosyl alcohol;n-hexacosanol

Chemical Property of 1-Hexacosanol

Chemical Property:

• Appearance/Colour: white powder
• Vapor Pressure: 1.85E-15mmHg at 25°C
• Melting Point: 78-80 °C
• Refractive Index: 1.47
• Boiling Point: 411.9 °C at 760 mmHg
• PKA: 15.20±0.10(Predicted)
• Flash Point: 139.2 °C
• PSA: 20.23000
• Density: 0.84 g/cm³
• LogP: 9.36100
• Storage Temp.: 2-8°C
• Solubility.: Chloroform (Slightly), Hexanes (Slightly, Heated, Sonicated)
• XLogP3: 12.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 24
• Exact Mass: 382.417466342
• Heavy Atom Count: 27
• Complexity: 238

Purity/Quality:

99% ^*data from raw suppliers

1-Hexacosanol ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Other Classes -> Alcohols and Polyols, Other
• Canonical SMILES: CCCCCCCCCCCCCCCCCCCCCCCCCCO
• Uses: 1-Hexacosanol shows potential application to reducing parkinson’s symptoms. Shown to contribute to the modulation of the release of proinflammatory mediators.

Technology Process of 1-Hexacosanol

There total 15 articles about 1-Hexacosanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 17.66%

icosane (112-95-8) + n-docosane (629-97-0) + n-hexacosane (630-01-3) + Tridecane (629-50-5) + octadecane (593-45-3) + tetracosane (646-31-1) + octacosane (630-02-4) + n-triacontane (638-68-6) → 1-octadecanol (112-92-5) + n-eicosanol (629-96-9) + melissyl alcohol (593-50-0) + 1-docosanol (661-19-8) + tetracosyl alcohol (506-51-4) + hexacosyl alcohol (506-52-5) + octacosyl alcohol (557-61-9)

Guidance literature:

icosane; n-docosane; n-hexacosane; octadecane; tetracosane; octacosane; n-triacontane; With oxygen; at 30 - 50 ℃; for 0.5h; under 1575.16 Torr;

Tridecane; With titanium(IV) isopropylate; at 30 - 50 ℃; for 6.86667h; under 1575.16 - 3750.38 Torr;

With sulfuric acid; water; at 80 ℃; Product distribution / selectivity;

Reference yield: 12.4%

icosane (112-95-8) + n-docosane (629-97-0) + n-hexacosane (630-01-3) + octadecane (593-45-3) + tetracosane (646-31-1) + octacosane (630-02-4) + n-triacontane (638-68-6) → 1-octadecanol (112-92-5) + n-eicosanol (629-96-9) + melissyl alcohol (593-50-0) + 1-docosanol (661-19-8) + tetracosyl alcohol (506-51-4) + hexacosyl alcohol (506-52-5) + octacosyl alcohol (557-61-9)

Guidance literature:

icosane; n-docosane; n-hexacosane; octadecane; tetracosane; octacosane; n-triacontane; With oxygen; at 30 - 50 ℃; for 3h; under 1575.16 - 3675.37 Torr;

With sulfuric acid; water; Product distribution / selectivity;

Reference yield:

C33H60O → hexacosyl alcohol (506-52-5)

Guidance literature:

With hydrogen; 5%-palladium/activated carbon; In ethyl acetate; at 25 ℃;

upstream raw materials:

hexacosanoic acid ethyl ester

methyl hexacosanoate

n-hexacosanol acetate

hexacosanoic acid sodium salt

Downstream raw materials:

1-Brom-hexacosan

1-hexacosanoic acid

hexacosanal

dopentacontane

Refernces

• 1、 -. "PROCESS FOR THE PREPARATION OF ALIPHATIC PRIMARY ALCOHOLS AND RELATED INTERMEDIATES IN SUCH PROCESS". Page/Page column 8. . Retrieved 2010/02/11.
• 2、 Zakharkin, L. I.,Churilova, I. M.,Anikina, E. V.. "Synthesis of even C24-C30 primary normal aliphatic alcohols from cyclododecanone". . p. 65 - 67. Retrieved 2007/10/02.