5-Amino-2-ethoxybenzenesulfonic acid

Base Information

• Chemical Name: 5-Amino-2-ethoxybenzenesulfonic acid
• CAS No.: 6375-02-6
• Molecular Formula: C8H11NO4S
• Molecular Weight: 217.246
• Hs Code.: 2922299090
• European Community (EC) Number: 228-929-9
• NSC Number: 508871
• UNII: A9PJ3G8CLF
• DSSTox Substance ID: DTXSID50213183
• Nikkaji Number: J8.394A
• Wikidata: Q72436536
• Mol file: 6375-02-6.mol

Synonyms:5-Amino-2-ethoxybenzenesulfonic acid;6375-02-6;5-AMINO-2-ETHOXY-BENZENESULFONIC ACID;6-Ethoxymetanilic acid;p-Phenetidine-3-sulfonic acid;5-Amino-2-ethoxybenzenesulphonic acid;NSC-508871;Benzenesulfonic acid, 5-amino-2-ethoxy-;EINECS 228-929-9;A9PJ3G8CLF;Metanilic acid, 6-ethoxy-;SCHEMBL5677336;DTXSID50213183;NSC508871;AKOS015964890;NSC 508871;SB38072;4-amino-1-ethoxy-benzene-2-sulphonic acid;CS-0454444

Chemical Property of 5-Amino-2-ethoxybenzenesulfonic acid

Chemical Property:

• Vapor Pressure: 3.48E-14mmHg at 25°C
• Refractive Index: 1.637
• Boiling Point: 596.3°C at 760 mmHg
• Flash Point: 314.4°C
• PSA: 98.00000
• Density: 1.401 g/cm³
• LogP: 2.57620
• XLogP3: 0.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 217.04087901
• Heavy Atom Count: 14
• Complexity: 272

Purity/Quality:

98%min ^*data from raw suppliers

5-Amino-2-ethoxy-benzenesulfonicacid 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC1=C(C=C(C=C1)N)S(=O)(=O)O

Technology Process of 5-Amino-2-ethoxybenzenesulfonic acid

There total 7 articles about 5-Amino-2-ethoxybenzenesulfonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Ethoxyaniline (156-43-4) → 1-amino-4-ethoxybenzene-3-sulphonic acid (6375-02-6)

Guidance literature:

With sulfuric acid; In 1,2-dichloro-benzene; at 175 - 180 ℃; Yield given; 3-5 h;

Reference yield:

5-acetylamino-2-ethoxy-benzenesulfonic acid → 1-amino-4-ethoxybenzene-3-sulphonic acid (6375-02-6)

Guidance literature:

With alkaline solution;

Reference yield:

4-ethoxyacetanilide (62-44-2,105931-34-8) → 1-amino-4-ethoxybenzene-3-sulphonic acid (6375-02-6)

Guidance literature:

Multi-step reaction with 2 steps

1: concentrated sulfuric acid

2: diluted sulfuric acid

With sulfuric acid;

upstream raw materials:

4-Ethoxyaniline

sulfuric acid

4-ethoxyacetanilide

Refernces

• 1、 -. "2,4-diamino-6-fluorotriazine disazo reactive dyestuffs". . . Retrieved 2008/06/13.
• 2、 -. "Fiber-reactive disazo brown dye having vinylsulfone-type reactive group". . . Retrieved 2008/06/13.