Butan-2-amine hydrochloride

Base Information

• Chemical Name: Butan-2-amine hydrochloride
• CAS No.: 10049-60-2
• Molecular Formula: C₄H₁₂N*Cl
• Molecular Weight: 109.599
• European Community (EC) Number: 233-176-4
• DSSTox Substance ID: DTXSID90905550
• NSC Number: 61473
• Mol file: 10049-60-2.mol

Synonyms:butan-2-amine hydrochloride;10049-60-2;MFCD04040036;(S)-(-)-sec-Butylamine hydrochloride;2-butanamine hydrochloride;SCHEMBL4240152;(S)-2-butylamine Hydrochloride;DTXSID90905550;NSC61473;NSC-61473;SB44877;SB45538;Butan-2-amine--hydrogen chloride (1/1);SY059203;WS-02292

Chemical Property of Butan-2-amine hydrochloride

Chemical Property:

• Vapor Pressure: 175mmHg at 25°C
• Melting Point: 152-153 °C
• Boiling Point: 62.9°Cat760mmHg
• Flash Point: 25.2°C
• PSA: 27.64000
• Density: g/cm³
• LogP: -2.96920
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 109.0658271
• Heavy Atom Count: 6
• Complexity: 19.6

Purity/Quality:

98%,99%, ^*data from raw suppliers

SEC-BUTYLAMMONIUM CHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(C)N.Cl

Technology Process of Butan-2-amine hydrochloride

There total 7 articles about Butan-2-amine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

diphenylphosphinic 1-methylpropylamide (76716-18-2) → sec-butylamine hydrochloride (10049-60-2,31519-50-3,31519-51-4)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; Ambient temperature;

DOI:10.1055/s-1980-29184

Reference yield: 66.0%

C13H28NO5P (102095-57-8) → sec-butylamine hydrochloride (10049-60-2,31519-50-3,31519-51-4)

Guidance literature:

With hydrogenchloride; In benzene; for 12h; Ambient temperature;

Reference yield: 44.0%

1-<(1-methylpropylidene)amino>-3-phenyl-4-methyl-5-methoxypyrazole (142310-24-5) → sec-butylamine hydrochloride (10049-60-2,31519-50-3,31519-51-4) + 3-phenyl-4-methyl-5-methoxypyrazole (39513-12-7)

Guidance literature:

With hydrogenchloride; hydrogen; palladium on activated charcoal; In methanol; under 2585.7 Torr; Ambient temperature;

upstream raw materials:

sec-Butyl-phosphorimidic acid triethyl ester

diphenylphosphinic 1-methylpropylamide

C₁₃H₂₈NO₅P

1-<(1-methylpropylidene)amino>-3-phenyl-4-methyl-5-methoxypyrazole

Downstream raw materials:

sec-butyl isocyanate

1,7-dihydro-2-methyl-1-(1-methylpropyl)-7-phenyl-6H-purin-6-one

3-sec-butylamino-1,2-benzisothiazole-1,1-dioxide

N-sec-Butyl-3,3,3-trifluoro-2-methoxy-2-phenyl-propionamide

Refernces

• 1、 Adembri, G.,Camparini, A.,Ponticelli, F.,Scotton, M.. "Hydrogenolysis of 1-Aminopyrazoles: Synthesis of Primary and Secondary Alkylamines ". . p. 321 - 326. Retrieved 2007/10/02.
• 2、 Koziara, Anna,Osowska-Pacewicka, Krystyna,Zawadzki, Stefan,Zwierzak, Andrzej. "One-Pot Transformation of Alkyl Bromdes into Primary Amines via the Staudinger Reaction". . p. 202 - 204. Retrieved 2007/10/02.