Lupinane

Base Information

• Chemical Name: Lupinane
• CAS No.: 491-43-0
• Molecular Formula: C10H19N
• Molecular Weight: 153.26
• Mol file: 491-43-0.mol

Synonyms:

Chemical Property of Lupinane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Lupinane

There total 22 articles about Lupinane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

1-(Pent-4-enyl)-2-(trimethylsilyl)piperidine (145388-39-2) → 5-Methyl-1-azabicyclo<4.4.0>decane (491-43-0,4772-55-8,5581-88-4,5581-89-5,18396-98-0,31085-23-1,31097-79-7,145416-69-9)

Guidance literature:

With naphthalene-1,4-dicarbonitrile; In isopropyl alcohol; for 3h; Irradiation;

DOI:10.1016/S0040-4039(00)79035-6

Reference yield:

diethyl 4-oxo-4H-quinolizine-1,3-dicarboxylate (54401-76-2) → 5-Methyl-1-azabicyclo<4.4.0>decane (491-43-0,4772-55-8,5581-88-4,5581-89-5,18396-98-0,31085-23-1,31097-79-7,145416-69-9)

Guidance literature:

With 1,4-dioxane; copper oxide-chromium oxide; at 260 ℃; under 250073 Torr; Hydrogenation;

DOI:10.1021/ja01607a064

Reference yield:

diethyl 4-oxo-4H-quinolizine-1,3-dicarboxylate (54401-76-2) → 1-methylquinolizidine (491-43-0,4772-55-8,5581-88-4,5581-89-5,18396-98-0,31085-23-1,31097-79-7,145416-69-9) + 5-Methyl-1-azabicyclo<4.4.0>decane (491-43-0,4772-55-8,5581-88-4,5581-89-5,18396-98-0,31085-23-1,31097-79-7,145416-69-9)

Guidance literature:

With 1,4-dioxane; copper oxide-chromium oxide; at 260 ℃; under 250073 Torr; Hydrogenation;

DOI:10.1021/ja01607a064

upstream raw materials:

(1S,9aR)-1-(aminomethyl)-(octahydro-2H-quinolizine)

(9aR)-1t-(toluene-4-sulfonyloxymethyl)-(9ar)-octahydro-quinolizin

lupinine

diethyl 4-oxo-4H-quinolizine-1,3-dicarboxylate

Downstream raw materials:

9-epi-lupinyliden-fluorene

epi-lupinina

Refernces

• 1、 Pandey, Ganesh,Reddy, G. Devi. "Stereoselectivity in the cyclisation of photoinduced electron transfer (PET) generated cyclic α -amino radicals: First general stereoselective entry to 1-azabicyclo (m:n:o) alkane systems". . p. 6533 - 6536. Retrieved 2007/10/02.